FB2024_03 , released June 25, 2024
Allele: Dmel\Gug14967
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General Information
Symbol
Dmel\Gug14967
Species
D. melanogaster
Name
FlyBase ID
FBal0196226
Feature type
allele
Associated gene
Dmel\Gug
Associated Insertion(s)
P{lacW}Gug14967
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Charroux et al., 2006)
Progenitor genotype
Associated Insertion(s)
P{lacW}Gug14967
Cytology
Description

Insertion of a P{lacW} element at position 842898 in the 5'UTR of the Gug gene.

(Charroux et al., 2006)
Allele components
Component
Use(s)
Inserted element
P{lacW}
Encoded product / tool
lacZ
Tagged with
Tag:NLS(P)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Gug14967 clones in the wing lead to the induction of extra wing-vein tissue.

      (Charroux et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      Gug14967/Gug[+] is an enhancer of wing vein | ectopic phenotype of rlSem

      (Charroux et al., 2006)

      Gug14967 is an enhancer of eye photoreceptor cell | increased number | somatic clone phenotype of aosΔ7

      (Charroux et al., 2006)

      Gug14967/Gug[+] is an enhancer of interommatidial bristle phenotype of rhohs.sev

      (Charroux et al., 2006)

      Gug14967/Gug[+] is an enhancer of ommatidium phenotype of rhohs.sev

      (Charroux et al., 2006)
      Suppressor of
      Statement
      Reference

      Gug14967 is a suppressor of interommatidial bristle phenotype of aosGMR.PC

      (Charroux et al., 2006)

      Gug14967 is a suppressor of ommatidium phenotype of aosGMR.PC

      (Charroux et al., 2006)
      Other
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The rough eye phenotype seen when flies express one copy of rhohs.sev is enhanced when these flies are heterozygous for Gug14967.

      The rough eye phenotype seen when flies express one copy of argosGMR.PC is partially suppressed in Gug14967 heterozygotes.

      The ectopic wing vein material phenotype of flies expressing rlSem is enhanced in Gug14967 heterozygotes.

      Although extra wing vein material is induced in Gug14967 clones, wing vein differentiation is blocked in vn10567 rhoPΔ5 Gug14967 triple mutant clones.

      The extra photoreceptor cell phenotype of argosΔ7 clones is enhanced in argosΔ7 Gug14967 clones, with a greater percentage of ommatidia showing supernumerary photoreceptor cells. These extra photoreceptor cells are never R8 cells. In contrast, ru1 rho7M43 Gug14967 argosΔ7 mutant clones lack photoreceptor cells.

      (Charroux et al., 2006)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Atro14967
      (Charroux et al., 2006)
      Gug14967
      Name Synonyms
      Secondary FlyBase IDs
        References (1)