FB2024_03 , released June 25, 2024
Allele: Hsap\CDIPTPis.PW
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General Information
Symbol
Hsap\CDIPTPis.PW
Species
H. sapiens
Name
Phosphatidylinositol synthase promoter construct of Wang
FlyBase ID
FBal0196217
Feature type
allele
Associated gene
Hsap\CDIPT
Associated Insertion(s)
Carried in Construct
P{Pis-CDIPT.W}
Key Links
Transgenic product class
wild_type
(Wang and Montell, 2006)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wang and Montell, 2006)
Mutagen
in vitro construct
(Wang and Montell, 2006)
Progenitor genotype
Carried in construct
P{Pis-CDIPT.W}
Cytology
Description

A 2kb Pis genomic region (corresponding to -2100 to -10bp of the Pis gene) drives expression of Hsap\CDIPT.

(Wang and Montell, 2006)
Allele components
Component
Use(s)
Regulatory region(s)
Pis
Encoded product / tool
Hsap\CDIPT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Hsap\CDIPTPis.PW is a suppressor of lethal | embryonic stage phenotype of Pis1

      (Wang and Montell, 2006)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Hsap\CDIPTPis.PW is a suppressor of eye | somatic clone phenotype of Pis1

      (Wang and Montell, 2006)

      Hsap\CDIPTPis.PW is a suppressor of eye photoreceptor cell | somatic clone phenotype of Pis1

      (Wang and Montell, 2006)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Expression of Hsap\CDIPTPis.PW rescues both the embryonic lethality and the eye phenotype of Pis1 flies. Rescue of eyes is complete as the ERG response of rescued flies is indistinguishable from wild type.

      (Wang and Montell, 2006)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hsap\CDIPTPis.PW
      Name Synonyms
      Phosphatidylinositol synthase promoter construct of Wang
      Secondary FlyBase IDs
        References (1)