Imprecise excision of the P{EP} element, resulting in an ~11kb deletion around exon 0.
At 25[o]C the fraction and net velocity vector of motile osk ribonucleoproteins (RNPs) in homozygous or klarYG3/klar1 oocytes is not significantly different from wild type. However the mean speed is slightly, but significantly reduced and RNP travel distance is significantly increased. At 18[o]C, the fraction of motile osk RNPs in the mutant oocytes is double that seen in control oocytes in a given imaging period. The RNP travel distance is significantly increased compared to wild type at this temperature.
The hatching rate of embryos derived from homozygous females is reduced compared to those derived from wild-type females, at both 25[o]C and 18[o]C (the phenotype is more severe at 18[o]C). Many embryos laid by homozygous females are arrested before the syncytial blastoderm stage or have abnormal nuclear distribution around cellularisation. Most unhatched embryos fail to form a cuticle and those that do, show defects in overall patterning.
The nuclei of developing photoreceptor cells are mispositioned in mutant eye imaginal discs, with many nuclei being found basally (the nuclei are apical in wild-type discs).
In klarYG3 mutant eye discs, nuclei are present in both apical and basal sections, indicating disrupted nuclear migration; nuclei are also found in the optical nerve.
klarYG3 embryos show aberrant lipid droplet transport.
klarYG3 has some die during embryonic stage | maternal effect | cold sensitive phenotype, suppressible | maternal effect | partially by osk[+]/oskA87
klarYG3/klar1 has some die during embryonic stage | maternal effect phenotype, suppressible | maternal effect | partially by osk[+]/oskA87
