FB2024_03 , released June 25, 2024
Allele: Dmel\mamEP2022.A
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General Information
Symbol
Dmel\mamEP2022.A
Species
D. melanogaster
Name
FlyBase ID
FBal0194266
Feature type
allele
Associated gene
Dmel\mam
Associated Insertion(s)
P{EP}mamEP2022.A
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Alexander et al., 2006)
Progenitor genotype
Associated Insertion(s)
P{EP}mamEP2022.A
Cytology
Description

The P{EP} element is inserted approximately 100 base pairs upstream of the transcribed region of mam and is orientated to express mam in the presence of Scer\GAL4.

(Alexander et al., 2006)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of mamN.Scer\UAS under the control of Scer\GAL4pnr-MD237 results in a 100% penetrant loss of many microchaetes along the central anterior/posterior axis of the notum. This phenotype is partially suppressed in flies also heterozygous for mamEP2022.A. (Flies heterozygous for mamEP2022.A and Scer\GAL4pnr-MD237 produce notal bristle phenotypes similar to those in flies heterozygous for Scer\GAL4pnr-MD237 alone.)

      Expression of mamH.Scer\UAS under the control of Scer\GAL4C96 produces nicks around the wing margin with 100% penetrance. This phenotype is partially suppressed in flies also heterozygous for mamEP2022.A. (Flies heterozygous for both mamEP2022.A and Scer\GAL4C96 do not exhibit any wing phenotypes.)

      Expression of mamH.Scer\UAS under the control of Scer\GAL4309 elicits an increase in the number of bristles at the site of the posterior notopleural macrochaete. This phenotype is partially suppressed in flies also heterozygous for mamEP2022.A. (Flies heterozygous for both mamEP2022.A and Scer\GAL4309 do not have posterior notopleural macrochaete phenotypes.)

      (Alexander et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      mamEP2022.A
      Name Synonyms
      Secondary FlyBase IDs
        References (1)