Amino acid replacement: D132N.
Adult-specific (using TubGAL80ts) expression of dcoD132N.Scer\UAS driven by Scer\GAL4P2.4.Pdf does not significantly affect circadian rhythmicity.
Expression of dcoD132N.Scer\UAS under the control of Scer\GAL4hs.2sev, results in planar polarity defects in the eye; these defects are stronger than those seen when a wild-type form of dco is overexpressed.
Scer\GAL4P2.4.Pdf/dcoD132N.UAS is a non-enhancer of abnormal locomotor rhythm phenotype of Scer\GAL4P2.4.Pdf, larkUAS.Tag:HA
Scer\GAL4dpp.blk1/dcoD132N.UAS is a non-enhancer of wing margin bristle | ectopic phenotype of Scer\GAL4dpp.blk1, fz22-2-2.UAS.Tag:MYC
Conditional adult-specific co-expression (using TubGAL80ts) of dcoScer\UAS.cKa (but not dcoD132N.Scer\UAS) results in arrhythmicity in flies with expression of larkScer\UAS.T:Ivir\HA1 driven by Scer\GAL4P2.4.Pdf.
Expression of dcoD132N.Scer\UAS in the eye, under the control of Scer\GAL4GMR.PF suppresses the WGMR.PG small eye phenotype.
Coexpression of fz22-2-2.Scer\UAS.T:Hsap\MYC and dcoD132N.Scer\UAS, under the control of Scer\GAL4dpp.blk1, at 18oC does not lead to an enhancement in the number of ectopic wing margin bristles compared to expression of fz22-2-2.Scer\UAS.T:Hsap\MYC alone. Coexpression of fz22-2-2.Scer\UAS.T:Hsap\MYC and dcoD132N.Scer\UAS at 25oC is not lethal.