Amino acid replacement: R245Q.
Nucleotide substitution: G?A.
The R245Q mutation is within the homeodomain of the expressed tup product.
G18862216A
G?A
R245Q | tup-PA; R245Q | tup-PB; R245Q | tup-PC
R245Q
CGG to CAG change in codon R245.
tupE52 die as embryos with a prominent dorsal hole.
tupE52/tup[+] is an enhancer of scutellar bristle | increased number phenotype of ChiE
Selected as: a dominant enhancer of the ChiE allele.