FB2024_03 , released June 25, 2024
Allele: Dmel\cpascrd2
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General Information
Symbol
Dmel\cpascrd2
Species
D. melanogaster
Name
FlyBase ID
FBal0191673
Feature type
allele
Associated gene
Dmel\cpa
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Johnson et al., 2008)
Mutagen
ethyl methanesulfonate
(Delalle et al., 2005)
Progenitor genotype
Cytology
Description

Amino acid replacement: V183D. Nucleotide substitution: T?A.

(Delalle et al., 2005)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      cpa[+]/cpascrd2 is an enhancer of abnormal planar polarity phenotype of Scer\GAL4GMR.PF, cindrRNAi.PC.PD.UAS

      (Johnson et al., 2008)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      cpa[+]/cpascrd2 is an enhancer of ommatidium phenotype of Scer\GAL4GMR.PF, cindrRNAi.PC.PD.UAS

      (Johnson et al., 2008)

      cpa[+]/cpascrd2 is an enhancer of pigment cell phenotype of Scer\GAL4GMR.PF, cindrRNAi.PC.PD.UAS

      (Johnson et al., 2008)

      cpa[+]/cpascrd2 is an enhancer of cone cell phenotype of Scer\GAL4GMR.PF, cindrRNAi.PC.PD.UAS

      (Johnson et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      A cpascrd2 background enhances the patterning defects found in Scer\GAL4GMR.PF>cindrdsRNA.PC.PD.Scer\UAS mutants. The mean interommatidial precursor cell number and the number of cone and/or 1[o] cell errors is increased in these double mutants.

      (Johnson et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Fails to complement

      cpaKG02261

      (Delalle et al., 2005)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      cpascrd2
      (Johnson et al., 2008)
      scrd2
      (Delalle et al., 2005)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)