UASt regulates expression of ΔN LamC, modeling a similar ΔN mutation in human Hsap\LMNA associated with muscular dystrophy.
UASt regulatory sequences drive expression of an N-terminally truncated form of LamC, which lacks the first 48 amino acids.
lethal, with Scer\GAL4unspecified
viable, with Scer\GAL4C57
embryonic/larval hypodermal muscle | larval stage, with Scer\GAL4C57
Expression of LamCΔN.Scer\UAS under the control of a ubiquitous Scer\GAL4 driver results in lethality.