FB2024_03 , released June 25, 2024
Allele: Dmel\sosief00514
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General Information
Symbol
Dmel\sosief00514
Species
D. melanogaster
Name
FlyBase ID
FBal0187304
Feature type
allele
Associated gene
Dmel\sosie
Associated Insertion(s)
PBac{WH}sosief00514
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
piggyBac activity
(Gene Disruption Project members and Exelixis, 2005)
Progenitor genotype
Associated Insertion(s)
PBac{WH}sosief00514
Cytology
Description
Allele components
Component
Use(s)
Inserted element
PBac{WH}
Regulatory region(s)
UAS
Also carries
FRT
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Homozygous and hemizygous females show defects in egg chamber formation, having compound egg chambers containing more than the normal 16 germ cells and more than one oocyte. The compound egg chambers appear to arise due to defective egg chamber packaging and not due to additional divisions of the germ cells: the two oocytes are separated from each other, later stage egg chambers contain nurse cell clusters of strongly differing ploidy and age, and the oocytes contain the normal number of four ring canals. Stage 10 egg chambers with binucleate nurse cells and degenerating ring canals are seen.

      Border cells migrate ahead of outer follicle cells in 65% of sosief00514/Df(3R)sosie egg chambers.

      Embryos derived from sosief00514/Df(3R)niki-sosie females are generally shorter than those from heterozygous siblings amd a small proportion of the eggs have a "dumpless" phenotype. The dorsal appendages are shorter and sometimes broader than normal.

      (Urwyler et al., 2012)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT Enhancer of
      Statement
      Reference

      sosief00514/CG13636[+] is a non-enhancer of follicle cell phenotype of kst01318/kst2

      (Urwyler et al., 2012)
      NOT Suppressor of
      Statement
      Reference

      sosief00514/CG13636[+] is a non-suppressor of follicle cell phenotype of kst01318/kst2

      (Urwyler et al., 2012)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      sosief00514/+ does not increase the penetrance of the follicle cell migration coordination defect (border cells migrating ahead of outer follicle cells) seen in kst2/kst01318 egg chambers.

      (Urwyler et al., 2012)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      sosief00514 is rescued by sosie+t8.4

      (Urwyler et al., 2012)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      CG13636f00514
      sie2
      (Urwyler et al., 2012)
      sosief00514
      Name Synonyms
      Secondary FlyBase IDs
        References (2)