FB2024_03 , released June 25, 2024
Allele: Ctet\tetXTNT-LC.UAS.cKa
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General Information
Symbol
Ctet\tetXTNT-LC.UAS.cKa
Species
C. tetani
Name
Saccharomyces cerevisiae UAS construct a of Keller
FlyBase ID
FBal0184268
Feature type
allele
Associated gene
Ctet\tetX
Associated Insertion(s)
Carried in Construct
P{UAS(-FRT)TeTxLC}
Also Known As
UAS-TNT
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
FLPase
(Keller et al., 2002)
Progenitor genotype
Ctet\tetXTNT-LC.FRT.UAS
(Keller et al., 2002)
Carried in construct
P{UAS(-FRT)TeTxLC}
Cytology
Description

FRT-w+mW.hs cassette has been excised, bringing TNT-LC coding sequences under the control of UAS sequences.

(Keller et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
TNT-LC
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of Ctet\TeTxLCScer\UAS.cKa under the control of Scer\GAL4ple.PF results in elevated sleep, which increases upon treatment with 5-HTP.

      The baseline levels of daily sleep in flies expressing Ctet\TeTxLCScer\UAS.cKa (under the control of Scer\GAL4Ddc.PL) do not change significantly in response to 5-HTP treatment.

      (Yuan et al., 2006)

      Expression of Ctet\TeTxLCScer\UAS.cKa under the control of Scer\GAL4Ddc.PL results in a flight defective phenotype in 45% of flies. The flies that show the flight phenotype also show flight physiology phenotypes in the indirect flight muscles as these muscles are unable to initiate flight spike patterns and display abnormal spontaneous bursting activity.

      (Banerjee et al., 2004)

      Ctet\TeTxLCScer\UAS.cKa mutants are homozygous lethal at 250C but not at 180C. Flies expressing Ctet\TeTxLCScer\UAS.cKa under the control of Scer\GAL4GMR.PF show no preference for sectors with black stripes in an optomotor, while control flies show a preference for stripes.

      (Keller et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (5)
      Reported As
      Symbol Synonym
      Ctet\TeTxLCScer\UAS.cKa
      Ctet\TeTxLCUAS.cKa
      Ctet\tetXTNT-LC.UAS.cKa
      Ctet\tetXUAS.cKa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Keller
      (Keller et al., 2002)
      Secondary FlyBase IDs
        References (3)