FB2024_03 , released June 25, 2024
Allele: Dmel\pioUAS.cJa
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General Information
Symbol
Dmel\pioUAS.cJa
Species
D. melanogaster
Name
FlyBase ID
FBal0178436
Feature type
allele
Associated gene
Dmel\pio
Associated Insertion(s)
Carried in Construct
P{UAS-pio.cJa}
Key Links
Transgenic product class
cDNA
(Jazwinska et al., 2003)
wild_type
(Jazwinska et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Jazwinska et al., 2003)
wild_type
(Jazwinska et al., 2003)
Mutagen
in vitro construct
(Jazwinska et al., 2003)
Progenitor genotype
Carried in construct
P{UAS-pio.cJa}
Cytology
Description

UASt regulatory sequences drive expression of a 3.1kb cDNA corresponding to pio (EST: GH06654).

(Jazwinska et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
pio
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      Scer\GAL4btl.PS/pioUAS.cJa is a non-suppressor of embryonic/larval tracheal dorsal trunk phenotype of γCOP10

      (Grieder et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of pioScer\UAS.cJa under the control of Scer\GAL4btl.PS rescues the dorsal branch defects seen in γCop10 homozygous embryos. However, the narrowing of the dorsal trunk which is seen in γCop10 homozygous embryos is not rescued by expression of pioScer\UAS.cJa under the control of Scer\GAL4btl.PS.

      (Grieder et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4btl.PS/pioUAS.cJa rescues pio2R-16

      (Jazwinska et al., 2003)
      Comments

      Expression of pioScer\UAS.cJa under the regulation of Scer\GAL4btl.PS completely rescues the tracheal disruptions observed in embryos homozygous for pio2R-16, as well as embryos homozygous for Df(2R)Px2.

      (Jazwinska et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      pioScer\UAS.cJa
      pioUAS.cJa
      Name Synonyms
      Secondary FlyBase IDs
        References (2)