FlyBase Allele Report: Dmel\Eb1[42S11]

General Information

Symbol

Dmel\Eb1^42S11

Species

D. melanogaster

Name

FlyBase ID

FBal0176214

Feature type

allele

Associated gene

Dmel\Eb1

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

X ray

(Brumby et al., 2004)

ethyl methanesulfonate

(Brumby et al., 2004)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of pupal stage | recessive

(Brumby et al., 2004)

partially lethal - majority die (with Eb1⁰⁴⁵²⁴)

(Brumby et al., 2004)

some die during pupal stage | recessive

(Brumby et al., 2004)

Phenotype Manifest In

Detailed Description

Statement

Reference

Eb1^42S11/Eb1⁰⁴⁵²⁴ adult escapers so no have any gross abnormalities but generally die within a few days of eclosing, and female escapers are sterile.

(Brumby et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

Eb1^42S11, scrib¹/scrib⁵ has partially lethal phenotype

(Brumby et al., 2004)

Phenotype Manifest In

Suppressor of

Statement

Reference

Eb1^42S11/Eb1[+] is a suppressor of eye phenotype of CycE^JP

(Brumby et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

"X ray" was stated as tentative. "ethyl methanesulfonate" was stated as tentative. Transcription of the Eb1 gene is disrupted in Eb1^42S11 mutants.

(Brumby et al., 2004)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

42S11

(Brumby et al., 2004)

Eb1^42S11

S(DmcycE^JP)2.5^42S11

(Brumby et al., 2004)

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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