FlyBase Allele Report: Dmel\Su(var)3-7[P12]

General Information

Symbol

Dmel\Su(var)3-7^P12

Species

D. melanogaster

Name

FlyBase ID

FBal0175790

Feature type

allele

Associated gene

Dmel\Su(var)3-7

Associated Insertion(s)

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

Mutagen

Delta2-3 transposase

(Bushey and Locke, 2004)

Progenitor genotype

P{PZ}CtBP⁰³⁴⁶³

(Bushey and Locke, 2004)

Cytology

Description

Imprecise excision of the P{PZ}CtBP⁰³⁴⁶³ element, resulting in a deletion of nucleotides 2990-3445 (coordinates relative to GenBank accession number X52187.1) which deletes sequences encoding Su(var)3-7 amino acids 896 to 1020.

(Bushey and Locke, 2004)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

deletion

3R:13,267,987..13,268,442 [+]

Comment:

Imprecise excision of the P{PZ}CtBP⁰³⁴⁶³ element, resulting in a deletion of nucleotides 2610-2622 (coordinates relative to GenBank accession number X52187.1).

(Bushey and Locke, 2004)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

suppressor of variegation, with In(1)w^m4

(Bushey and Locke, 2004)

suppressor of variegation, with P{hsp26-pt-T}39C-12

(Haynes et al., 2007)

suppressor of variegation, with P{hsp26-pt-T}39C-42

(Haynes et al., 2007)

suppressor of variegation, with P{hsp26-pt-T}118E-10

(Haynes et al., 2007)

suppressor of variegation, with P{hsp26-pt-T}gw^39C-33

(Haynes et al., 2007)

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

P{P-Sal}Pak3^P-Sal, P{lacW}Dplac, Su(var)3-7^P12 has suppressor of variegation phenotype

(Bushey and Locke, 2004)

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

When P{P-Sal}89D is present, the w gene of the P{lacW}ci^Dplac insertion variegates, resulting (in a w^- background) in an eye that is mostly white with a few patches of red ommatidia. This P-element-dependent silencing of P{lacW}ci^Dplac is dominantly suppressed by Su(var)3-7^P12.

(Bushey and Locke, 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Su(var)3-7^P12

(Haynes et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

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