FB2024_03 , released June 25, 2024
Allele: Dmel\NPFRc01896
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General Information
Symbol
Dmel\NPFRc01896
Species
D. melanogaster
Name
FlyBase ID
FBal0160150
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
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Disease-implicated variant(s)
 
Phenotypic Data
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NPFRlexA/NPFRc01896 males have significantly increased courtship towards males, compared to controls.

NPFRc01896 homozygous adult ab3A neurons present a significant decrease in the frequency of odor-evoked electrophysiological spikes in response to ethyl butyrate and apple odor and do not display the normal sexual dimorphism regarding odor-evoked electrophysiological response, by which young males (1-3 days old) exhibit a significantly higher frequency of ethyl butyrate-evoked electrophysiological spikes than age-matched females, as compared to controls.

NPFRc01896/Df(3R)Tpl3 transheterozygous adult ab3A neurons present a significant decrease in the frequency of ethyl butyrate-evoked electrophysiological spikes, as compared to each heterozygous and wild-type controls.

NPFRc01896 mutant larvae fail to form short-term olfactory memory following training with 0.02 M fructose, with their performance being significantly impaired compared to controls; this effect does not occur when larvae are trained using 2 M fructose, even when they are starved beforehand. They have no innate difference in odor or sugar preference compared to controls.

Food deprived NPFR1c01896 flies exhibit an impaired appetitive memory.

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Complementation and Rescue Data
Comments

The decreased frequency of ethyl butyrate-evoked electrophysiological spikes observed in NPFRc01896 homozygous adult ab3A neurons is rescued by the expression of NPFRScer\UAS.RD, but not NPFRScer\UAS.RB, under the control of Scer\GAL4Or22a.7.717.

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Synonyms and Secondary IDs (3)
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    References (8)