FB2024_03 , released June 25, 2024
Allele: Dmel\eveΔRP2B
Open Close
General Information
Symbol
Dmel\eveΔRP2B
Species
D. melanogaster
Name
FlyBase ID
FBal0155321
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

Sequence from +8.0kb to +9.2kb (coordinates relative to the eve transcription start site) of the eve genomic region has been deleted, thus sequences from -6.4kb to +8.0kb of eve are present.

Allele components
Component
Use(s)
Regulatory region(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Homozygous Df(2R)eve embryos carrying both eveΔRP2A and eveΔRP2B show defects in the RP2, aCC and pCC neurons.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Partially rescues
Comments

Two copies of eveΔRP2B fully rescue segmentation function in eve null mutants. However, at the extended germband stage, eve expression in the mesoderm is often weak or missing.

Homozygous Df(2R)eve embryos carrying eveΔRP2A and eveΔRP2B show defects in the RP2, aCC and pCC neurons.

Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
eveΔRP2B
Name Synonyms
Secondary FlyBase IDs
    References (1)