FB2024_03 , released June 25, 2024
Allele: Dmel\nkdD201A.UAS.Tag:MYC
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General Information
Symbol
Dmel\nkdD201A.UAS.Tag:MYC
Species
D. melanogaster
Name
FlyBase ID
FBal0146981
Feature type
allele
Associated gene
Dmel\nkd
Associated Insertion(s)
Carried in Construct
P{UAS-nkd.D201A.mycC}
Key Links
Transgenic product class
missense_variant
(Rousset et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
missense_variant
(Rousset et al., 2002)
Mutagen
in vitro construct
(Rousset et al., 2002)
Progenitor genotype
Carried in construct
P{UAS-nkd.D201A.mycC}
Cytology
Description

UASt regulatory sequences drive expression of a mutated form of nkd, which is tagged at the C-terminal end with Tag:MYC.

(Waldrop et al., 2006)

UAS regulatory sequences drive expression of a mutated form of nkd (carries the amino acid replacement D201A).

(Rousset et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
UASt
Encoded product / tool
nkd
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      nkdD201A.UAS.Tag:MYC/Scer\GAL4da.G32 rescues nkd3/nkd2

      (Rousset et al., 2002)
      Partially rescues

      nkdD201A.UAS.Tag:MYC/Scer\GAL4da.G32 partially rescues nkd3/nkd2

      (Waldrop et al., 2006)
      Comments

      Expression of nkdD201A.Scer\UAS.T:Hsap\MYC under the control of Scer\GAL4da.G32 largely rescues the cuticle defects of nkd2/nkd3 embryos and adult viability is restored.

      (Waldrop et al., 2006)

      Rescues the cuticle defects of nkd2/nkd3 embryos when expressed under the control of Scer\GAL4da.G32.

      (Rousset et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      NkdD201/mycC
      (Waldrop et al., 2006)
      nkdD201A.Scer\UAS.T:Hsap\MYC
      nkdD201A.Scer\UAS
      nkdD201A.UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (2)