FB2024_03 , released June 25, 2024
Allele: Dmel\pain+t8.5
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General Information
Symbol
Dmel\pain+t8.5
Species
D. melanogaster
Name
FlyBase ID
FBal0146952
Feature type
allele
Associated gene
Dmel\pain
Associated Insertion(s)
Carried in Construct
P{pain-rescue}
Also Known As
pain-genome
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Tracey et al., 2003)
wild_type
(Tracey et al., 2003)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Tracey et al., 2003)
wild_type
(Tracey et al., 2003)
Mutagen
in vitro construct
(Tracey et al., 2003)
Progenitor genotype
Carried in construct
P{pain-rescue}
Cytology
Description

Consists of an 8.5kb genomic fragment that includes the pain gene and 2.0kb of upstream sequence.

(Tracey et al., 2003)
Allele components
Component
Use(s)
Regulatory region(s)
pain
pain_rescue
Encoded product / tool
pain
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
2R:24,921,504..24,930,269 [-]
Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator.

(Tracey et al., 2003)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      pain+t8.5 rescues painGAL4

      (Sakai et al., 2012)

      pain+t8.5 rescues painEP2621

      (Sakai et al., 2012)

      pain+t8.5 rescues painEP2451

      (Xu et al., 2006)
      Comments

      Allyl- or benzl-isothiocyanate inhibition of sucrose-induced proboscis extension is rescued in painEP2451 pain+t8.5 mutants.

      The isothiocyanate avoidance phenotype observed in painEP2451 mutants is rescued upon expression of pain+t8.5.

      Allyl- or benzl-isothiocyanate inhibition of sucrose-induced proboscis extension is rescued in painEP2451 pain+t8.5 mutants, with these flies exhibiting near wild-type levels of allyl- or benzl-isothiocyanate inhibition of the proboscis extension reflex.

      (Al-Anzi et al., 2006)

      pain+t8.5 rescues jump latencies in painEP2451/painEP2451 flies in both a CO[2] laser beam assay and in a heat plate assay.

      (Xu et al., 2006)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      pain+t8.5
      Name Synonyms
      Secondary FlyBase IDs
        References (6)