UASt regulatory sequences drive expression of a mutated form of E(spl)m7-HLH, which contains a double point mutation in the basic domain (same mutation as in the E(spl)m7-HLH sequences of E(spl)m7-HLHKNEQAct.VP16.UAS).
Expression of HLHm7KNEQ.Scer\UAS under the control of Scer\GAL4pnr-MD237 inhibits the formation of both macro- and micro-chaetae, resulting in a bald stripe in the centre of the adult thorax.
E(spl)m7-HLHKNEQ.UAS, Scer\GAL4pnr-MD237 is a suppressor of chaeta | ectopic phenotype of Scer\GAL4pnr-MD237, scUAS.cPa
Co-expression of HLHm7KNEQ.Scer\UAS and scScer\UAS.cPa under the control of Scer\GAL4pnr-MD237 results in adult flies with a bald stripe in the centre of the thorax (the formation of ectopic chaetae caused by expression of scScer\UAS.cPa under the control of Scer\GAL4pnr-MD237 is suppressed in these flies).