FB2024_03 , released June 25, 2024
Allele: Dmel\Sybhs.PB
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General Information
Symbol
Dmel\Sybhs.PB
Species
D. melanogaster
Name
heat shock construct of Bhattacharya
FlyBase ID
FBal0144498
Feature type
allele
Associated gene
Dmel\Syb
Associated Insertion(s)
Carried in Construct
P{hs-Syb.B}
Key Links
Transgenic product class
wild_type
(Bhattacharya et al., 2002)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Bhattacharya et al., 2002)
Mutagen
in vitro construct
(Bhattacharya et al., 2002)
Progenitor genotype
Carried in construct
P{hs-Syb.B}
Cytology
Description

An Hsp70 promoter drives expression of the open reading frame of the Syb-a isoform.

(Bhattacharya et al., 2002)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Syb
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Sybhs.PB is a suppressor of neuromuscular junction phenotype of nSybΔF33B

      (Bhattacharya et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The on and off transients of the electroretinogram are restored in mosaic animals in which the eyes are homozygous for n-sybΔF33B if they are also expressing Sybhs.PB. Evoked responses at the n-sybΔF33B neuromuscular junction are partially restored by expression of Sybhs.PB.

      (Bhattacharya et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Sybhs.PB rescues Syb21-15

      (Bhattacharya et al., 2002)
      Comments

      The failure of eye development seen in mosaic flies in which the eyes are homozygous for Syb21-15 is rescued by expression of Sybhs.PB.

      (Bhattacharya et al., 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Sybhs.PB
      Name Synonyms
      heat shock construct of Bhattacharya
      (Bhattacharya et al., 2002)
      Secondary FlyBase IDs
        References (1)