FB2024_03 , released June 25, 2024
Allele: Dmel\SoxNC2139
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General Information
Symbol
Dmel\SoxNC2139
Species
D. melanogaster
Name
FlyBase ID
FBal0141381
Feature type
allele
Associated gene
Dmel\SoxN
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Buescher et al., 2002)
Mutagen
ethyl methanesulfonate
(Buescher et al., 2002)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Neuroblast NB5-3 is lost in 12% of hemisegments in mutant embryos. Neuroblasts NB5-2, NB7-1 and NB1-1 are unaffected.

      (Buescher et al., 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      vndD38/+ ; SoxNC2139 embryos show an increased loss of ventral S1 neuroblasts compared to SoxNC2139 single mutants; NB5-2 is lost in 12% of hemisegments, NB7-1 shows 17% loss and NB1-1 shows 18% loss. ind16.2/+ ; SoxNC2139 embryos show an increased loss of neuroblasts compared to SoxNC2139 single mutants; NB5-3 is lost in 46% of hemisegments, and the RP2 neurons shows 99% loss.

      (Buescher et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      SoxNC2139
      (Chao et al., 2007)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)