FB2024_03 , released June 25, 2024
Allele: Dmel\BruceE12
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General Information
Symbol
Dmel\BruceE12
Species
D. melanogaster
Name
FlyBase ID
FBal0138572
Feature type
allele
Associated gene
Dmel\Bruce
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Vernooy et al., 2002)
Progenitor genotype
CG6293EP3731
(Vernooy et al., 2002)
Cytology
Description

Imprecise excision of the P{EP} in CG6293EP3731 has caused a deletion of the 3' end of Bruce, removing 1.5kb of Bruce genomic DNA.

(Vernooy et al., 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      BruceE12 is an enhancer of increased cell death phenotype of grimGMR.PH

      (Vernooy et al., 2002)

      BruceE12 is an enhancer of increased cell death phenotype of rprGMR.PH

      (Vernooy et al., 2002)
      NOT Enhancer of
      Statement
      Reference

      BruceE12 is a non-enhancer of increased cell death phenotype of hidGMR.PH

      (Vernooy et al., 2002)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      BruceE12 is an enhancer of eye phenotype of grimGMR.PH

      (Vernooy et al., 2002)

      BruceE12 is an enhancer of eye phenotype of rprGMR.PH

      (Vernooy et al., 2002)
      NOT Enhancer of
      Statement
      Reference

      BruceE12 is a non-enhancer of eye phenotype of hidGMR.PH

      (Vernooy et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The addition of BruceE12 enhances the cell death phenotype in the eye seen in grimGMR.PH or rprGMR.PH animals, but not WGMR.PH.

      (Vernooy et al., 2002)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      BruceE12
      Name Synonyms
      Secondary FlyBase IDs
        References (1)