FB2024_03 , released June 25, 2024
Allele: Dmel\NBC.lexA.UAS
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General Information
Symbol
Dmel\NBC.lexA.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0138461
Feature type
allele
Associated gene
Dmel\N
Associated Insertion(s)
Carried in Construct
P{UAS-N.BCLexA}
Key Links
Transgenic product class
Mutagen
Nature of the Allele
Transgenic product class
Mutagen
in vitro construct
(Kidd and Lieber, 2002)
Progenitor genotype
Carried in construct
P{UAS-N.BCLexA}
Cytology
Description

UAS regulatory sequences drive expression of N which is deleted for amino acids 1633-1692 and is tagged at the C-terminal end with the Ecol\lexA DNA-binding domain.

(Kidd and Lieber, 2002)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
N
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of NBC.Scer\UAS.T:Ecol\lexA under the control of Scer\GAL4da.G32 in a wild-type background produces no phenotype (in the peripheral nervous system).

      (Kidd and Lieber, 2002)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Scer\GAL4hh-Gal4/NBC.lexA.UAS is a suppressor of phenotype of l(2)gd1d7

      (Schneider et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Scer\GAL4hh-Gal4-mediated expression of NBC.Scer\UAS.T:Ecol\lexA suppresses the ectopic N activation phenotype (ectopic expression of wg) in the posterior of l(2)gd1d7 wing discs.

      (Schneider et al., 2013)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4da.G32/NBC.lexA.UAS partially rescues N264-47

      (Kidd and Lieber, 2002)
      Comments

      Expression of NBC.Scer\UAS.T:Ecol\lexA under the control of Scer\GAL4da.G32 partially rescues the N264-47 neurogenic phenotype.

      (Kidd and Lieber, 2002)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      NBC.Scer\UAS.T:Ecol\lexA
      NBC.lexA.UAS
      NBCLexA
      (Kidd and Lieber, 2002)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)