FlyBase Allele Report: Dmel\Notum[UAS.cGa]

General Information

Symbol

Dmel\Notum^UAS.cGa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of Giraldez

FlyBase ID

FBal0138439

Feature type

allele

Associated gene

Dmel\Notum

Associated Insertion(s)

Carried in Construct

P{UAS-Notum.G}

Also Known As

UAS-Notum

Key Links

Transgenic product class

cDNA

(Giraldez et al., 2002)

wild_type

(Giraldez et al., 2002)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

cDNA

(Giraldez et al., 2002)

wild_type

(Giraldez et al., 2002)

Mutagen

in vitro construct

(Giraldez et al., 2002)

Progenitor genotype

Carried in construct

P{UAS-Notum.G}

Cytology

Description

UASt regulatory sequences drive expression of a full length Notum cDNA.

(Giraldez et al., 2002)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Notum

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

wing, with Scer\GAL4^ap-md544

(Kirkpatrick et al., 2004)

wing margin | posterior, with Scer\GAL4^en-e16E

(Kreuger et al., 2004)

wing margin bristle | posterior, with Scer\GAL4^en-e16E

(Kreuger et al., 2004)

Detailed Description

Statement

Reference

Expression of Notum^Scer\UAS.cGa under the control of Scer\GAL4^ap-md544 results in the complete loss of wings in adult flies.

(Kirkpatrick et al., 2004)

Notum^Scer\UAS.cGa; Scer\GAL4^en-e16E flies lack some posterior wing margin bristles.

(Kreuger et al., 2004)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

Notum^UAS.cGa has wing margin | posterior phenotype, enhanceable by Scer\GAL4^en-e16E/dlp^UAS.Tag:HA

(Kreuger et al., 2004)

Suppressed by

Statement

Reference

Notum^UAS.cGa, Scer\GAL4^ap-md544 has wing phenotype, suppressible | partially by dlp¹/dlp[+]

(Kirkpatrick et al., 2004)

Enhancer of

Statement

Reference

Scer\GAL4^en-e16E/Notum^UAS.cGa is an enhancer of wing margin | posterior phenotype of dlp^UAS.Tag:HA

(Kreuger et al., 2004)

Additional Comments

Genetic Interactions

Statement

Reference

Heterozygosity for dlp¹ partially suppresses the wingless phenotype seen when Notum^Scer\UAS.cGa is expressed under the control of Scer\GAL4^ap-md544. Approximately 40% of such flies display a winglet on one side of the body, but are usually wingless on the other side. These winglets often display substantially normal wing patterning, although this phenotype is variable.

(Kirkpatrick et al., 2004)

Notum^Scer\UAS.cGa; dlp^{Scer\UAS.T:Ivir\HA1} Scer\GAL4^en-e16E have a scalloped posterior wing margin.

(Kreuger et al., 2004)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Notum^Scer\UAS.cGa

Notum^UAS.cGa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Giraldez

(Giraldez et al., 2002)

Secondary FlyBase IDs

References (4)

Report Sections

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