FlyBase Allele Report: Dmel\Scr[Tpl9]

General Information

Symbol

Dmel\Scr^Tpl9

Species

D. melanogaster

Name

FlyBase ID

FBal0138395

Feature type

allele

Associated gene

Dmel\Scr

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Caused by aberration

Df(3R)Tpl9

Cytology

Description

Deficiency breakpoint within Scr, such that the entire Scr transcription unit is removed, but the upstream Scr imaginal leg enhancer is still present.

(Southworth and Kennison, 2002)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal (with Scr^Antp-A41)

(Southworth and Kennison, 2002)

visible (with Scr⁴), with Dp(3;Y)77ab

(Southworth and Kennison, 2002)

visible (with Scr^Antp-A41)

(Southworth and Kennison, 2002)

visible (with Scr^Scx)

(Southworth and Kennison, 2002)

visible (with Scr^Wrv4)

(Southworth and Kennison, 2002)

visible | dominant

(Southworth and Kennison, 2002)

Phenotype Manifest In

mesothoracic leg (with Scr^Scx)

(Southworth and Kennison, 2002)

metathoracic leg (with Scr^Scx)

(Southworth and Kennison, 2002)

sex comb

(Southworth and Kennison, 2002)

sex comb (with Scr^Antp-A41)

(Southworth and Kennison, 2002)

sex comb (with Scr^Wrv4)

(Southworth and Kennison, 2002)

sex comb | ectopic (with Scr⁴), with Dp(3;Y)77ab

(Southworth and Kennison, 2002)

sex comb | ectopic (with Scr^Scx)

(Southworth and Kennison, 2002)

Detailed Description

Statement

Reference

Scr^Tpl9 heterozygous males (Df(3R)Tpl9 heterozygous males in which the haplolethality of Tpl has been rescued by Dp(3;3)Dfd^rv1) have an average of 8.8 sex comb teeth on the first leg (compared to 10.8 per leg in wild type). Scr^Antp-A41/Scr^Tpl9 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) show 13% viability and have an average of 1.8 sex comb teeth per first leg. Scr⁴/Scr^Tpl9; Dp(3;Y)77ab males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) have an average of 6.4 sex comb teeth per first leg. Scr^Wrv4/Scr^Tpl9 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) show 94% viability and have an average of 2.1 sex comb teeth per first leg. Scr^Scx/Scr^Tpl9 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) have an average of 8.7 ectopic sex comb teeth per second leg and an average of 5.0 ectopic sex comb teeth per third leg.

(Southworth and Kennison, 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scr^Tpl9 has visible | dominant phenotype, enhanceable by T(2;3)MAP3

(Southworth and Kennison, 2002)

Scr^Tpl9 has visible | dominant phenotype, enhanceable by T(2;3)bw^VDe3

(Southworth and Kennison, 2002)

Scr^Tpl9 has visible | dominant phenotype, enhanceable by T(2;3)P607

(Southworth and Kennison, 2002)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scr^Tpl9 has sex comb phenotype, enhanceable by T(2;3)MAP3

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, enhanceable by T(2;3)bw^VDe3

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, enhanceable by T(2;3)P607

(Southworth and Kennison, 2002)

NOT Enhanced by

Statement

Reference

Scr^Wrv4/Scr^Tpl9 has sex comb phenotype, non-enhanceable by z^11G3

(Southworth and Kennison, 2002)

Scr^Wrv4/Scr^Tpl9 has sex comb phenotype, non-enhanceable by z^a

(Southworth and Kennison, 2002)

Scr^Antp-A41/Scr^Tpl9 has sex comb phenotype, non-enhanceable by z¹

(Southworth and Kennison, 2002)

Scr^Antp-A41/Scr^Tpl9 has sex comb phenotype, non-enhanceable by z^a

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, non-enhanceable by Df(3R)Antp17

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, non-enhanceable by z^11G3

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, non-enhanceable by z¹

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, non-enhanceable by z^a

(Southworth and Kennison, 2002)

Scr^Wrv4/Scr^Tpl9 has sex comb phenotype, non-enhanceable by z¹

(Southworth and Kennison, 2002)

Scr^Antp-A41/Scr^Tpl9 has sex comb phenotype, non-enhanceable by z^11G3

(Southworth and Kennison, 2002)

NOT suppressed by

Statement

Reference

Scr^Wrv4/Scr^Tpl9 has sex comb phenotype, non-suppressible by z^11G3

(Southworth and Kennison, 2002)

Scr^Wrv4/Scr^Tpl9 has sex comb phenotype, non-suppressible by z¹

(Southworth and Kennison, 2002)

Scr^Wrv4/Scr^Tpl9 has sex comb phenotype, non-suppressible by z^a

(Southworth and Kennison, 2002)

Scr^Antp-A41/Scr^Tpl9 has sex comb phenotype, non-suppressible by z^11G3

(Southworth and Kennison, 2002)

Scr^Antp-A41/Scr^Tpl9 has sex comb phenotype, non-suppressible by z¹

(Southworth and Kennison, 2002)

Scr^Antp-A41/Scr^Tpl9 has sex comb phenotype, non-suppressible by z^a

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, non-suppressible by Df(3R)Antp17

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, non-suppressible by z^11G3

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, non-suppressible by z¹

(Southworth and Kennison, 2002)

Scr^Tpl9 has sex comb phenotype, non-suppressible by z^a

(Southworth and Kennison, 2002)

Additional Comments

Genetic Interactions

Statement

Reference

The average number of sex comb teeth per first leg in Scr^Tpl9 heterozygous males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) are reduced if they are also carrying T(2;3)P607, T(2;3)MAP3 or T(2;3)bw^VDe3. The average number of sex comb teeth per first leg in Scr^Tpl9 heterozygous males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) is not affected if they are also carrying Df(3R)Antp17. The average number of sex comb teeth per first leg in Scr^Tpl9 heterozygous males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) is not affected if they are also carrying z¹, z^a or z^11G3. The average number of sex comb teeth per first leg in Scr^Tpl9/Scr^Antp-A41 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) is not affected if they are also carrying z¹, z^a or z^11G3. The viability and average number of sex comb teeth per first leg in Scr^Tpl9/Scr^Wrv4 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) is not affected if they are also carrying z¹, z^a or z^11G3. Scr^Scx/Scr^Tpl9 males (in which the haplolethality of the Df(3R)Tpl9 chromosome has been rescued by Dp(3;3)Dfd^rv1) also carrying Pc²¹ have an average of 8.5 ectopic sex comb teeth per second leg and an average of 8.4 ectopic sex comb teeth per third leg.

(Southworth and Kennison, 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

Scr^Tpl9

Name Synonyms

Secondary FlyBase IDs

References (1)

Report Sections

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