FB2024_03 , released June 25, 2024
Allele: Dmel\S6kIIUAS.cRa
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General Information
Symbol
Dmel\S6kIIUAS.cRa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Rintelen
FlyBase ID
FBal0135821
Feature type
allele
Associated gene
Dmel\S6kII
Associated Insertion(s)
Carried in Construct
P{UAS-S6kII.R}
Key Links
Transgenic product class
wild_type
(Rintelen et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Rintelen et al., 2001)
Mutagen
in vitro construct
(Rintelen et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-S6kII.R}
Cytology
Description

UASt regulatory sequences drive expression of S6kII.

(Rintelen et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
S6kII
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      S6kScer\UAS.cMa; Scer\GAL4P2.4.Pdf adults have normal locomotor circadian rhythm.

      (Akten et al., 2009)

      Expression of S6kIIScer\UAS.cRa under the control of Scer\GAL4D42 results in a reduction in the absolute bouton number and in the bouton number per muscle area at the neuromuscular junction (at segment A3 in muscle 6/7) in larvae.

      (Fischer et al., 2009)

      Expression of S6kIIScer\UAS.cRa under the control of Scer\GAL4GMR.PF results in a rough eye phenotype.

      (Rintelen et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      Statement
      Reference

      S6kIIUAS.cRa, Scer\GAL4GMR.PF has visible phenotype, suppressible by Pdk14ΔEP/Pdk15ΔEP, Scer\GAL4GMR.PF

      (Rintelen et al., 2001)
      Phenotype Manifest In
      Suppressed by
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      Scer\GAL4tim.PE/S6kIIUAS.cRa partially rescues S6kIIign-Δ58-1

      (Akten et al., 2009)

      S6kIIUAS.cRa/Scer\GAL4tim.UAS partially rescues S6kIIign-Δ58-1

      (Akten et al., 2009)

      S6kIIUAS.cRa/Scer\GAL4P2.4.Pdf partially rescues S6kIIign-Δ58-1

      (Akten et al., 2009)

      S6kIIUAS.cRa/Scer\GAL4Toll-6-D42 partially rescues S6kIIign-Δ58-1

      (Fischer et al., 2009)
      Comments

      The defects in locomotor circadian rhythm seen in S6kIIign-Δ58-1 mutant adults are partially rescued by S6kIIScer\UAS.cRa with Scer\GAL4tim.PE, Scer\GAL4tim.Scer\UAS or Scer\GAL4P2.4.Pdf.

      (Akten et al., 2009)

      The increased absolute bouton number and bouton number per muscle area which is seen at the neuromuscular junction in S6kIIign-Δ58-1 larvae is significantly rescued by expression of S6kIIScer\UAS.cRa under the control of Scer\GAL4D42.

      (Fischer et al., 2009)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      S6kIIScer\UAS.cRa
      S6kIIUAS.cRa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Rintelen
      (Rintelen et al., 2001)
      Secondary FlyBase IDs
        References (6)