FB2024_03 , released June 25, 2024
Allele: Dmel\cu2
Open Close
General Information
Symbol
Dmel\cu2
Species
D. melanogaster
Name
FlyBase ID
FBal0135741
Feature type
allele
Associated gene
Dmel\cu
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
(Carpenter, 2002.4.2)
Progenitor genotype
Cytology

Polytene chromosomes normal.

(Carpenter, 2002.4.2)
Description

A base pair substitution followed by a single base pair deletion at positions 67/68 of exon 5 of the cu-RE isoform, which causes a premature translational stop at amino acid position 147 of the cu-PE protein.

(Grönke et al., 2009)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
complex_substitution
3R:11,207,426..11,207,427 [+]
Comment:

A base substitution (A to T) followed by a single base deletion causes premature translation termination.

Inserted_sequence:

T

(Grönke et al., 2009)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Induced on: In(3L)A54.

      (Carpenter, 2002.4.2)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      cu2
      (Grönke et al., 2009)
      Name Synonyms
      Secondary FlyBase IDs
        References (2)