FlyBase Allele Report: Dmel\l(3)L0539[EP3523]

General Information

Symbol

Dmel\l(3)L0539^EP3523

Species

D. melanogaster

Name

FlyBase ID

FBal0135681

Feature type

allele

Associated gene

l(3)L0539

Associated Insertion(s)

P{EP}l(3)L0539^EP3523

Carried in Construct

Also Known As

EP(3)3523

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Pena-Rangel et al., 2002, Tseng and Hariharan, 2002)

Progenitor genotype

Associated Insertion(s)

P{EP}l(3)L0539^EP3523

Cytology

Description

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3L:10,363,943..10,363,943 [+]

(Zhao et al., 2008, Pena-Rangel et al., 2002, Tseng and Hariharan, 2002)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal - all die before end of P-stage, with Scer\GAL4^386Y

(Zhao et al., 2008)

some die during pharate adult stage, with Scer\GAL4^386Y

(Zhao et al., 2008)

visible, with Scer\GAL4^CCAP.PP

(Zhao et al., 2008)

visible, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Phenotype Manifest In

eye, with Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

wing, with Scer\GAL4^CCAP.PP

(Zhao et al., 2008)

Detailed Description

Statement

Reference

Expression of l(3)L0539^EP3523 under the control of Scer\GAL4^Ccap.PP leads to wing expansion defects.

(Zhao et al., 2008)

Expression of l(3)L0539^EP3523 under the control of Scer\GAL4^ey.PH results in eyes that are strongly reduced in size. Flies expressing l(3)L0539^EP3523 under the control of Scer\GAL4^hs.2sev have wild-type eyes. Flies expressing l(3)L0539^EP3523 under the control of Scer\GAL4^en-e16E have wild-type wings.

(Tseng and Hariharan, 2002)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

Scer\GAL4^ey.PH, l(3)L0539^EP3523 has visible phenotype, non-suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

Scer\GAL4^pnr-MD237/l(3)L0539^EP3523 is an enhancer of visible phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Phenotype Manifest In

NOT suppressed by

Statement

Reference

Scer\GAL4^ey.PH, l(3)L0539^EP3523 has eye phenotype, non-suppressible by CycE^UAS.cLa, Scer\GAL4^ey.PH

(Tseng and Hariharan, 2002)

Enhancer of

Statement

Reference

Scer\GAL4^pnr-MD237/l(3)L0539^EP3523 is an enhancer of chaeta phenotype of pnr^MD237

(Pena-Rangel et al., 2002)

Other

Statement

Reference

Scer\GAL4^pnr-MD237, l(3)L0539^EP3523, pnr^MD237/pnr[+] has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, l(3)L0539^EP3523, pnr^MD237/pnr[+] has scutellar bristle phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, l(3)L0539^EP3523, pnr^MD237 has scutellum phenotype

(Pena-Rangel et al., 2002)

Scer\GAL4^pnr-MD237, l(3)L0539^EP3523, pnr^MD237 has scutellar bristle phenotype

(Pena-Rangel et al., 2002)

Additional Comments

Genetic Interactions

Statement

Reference

pnr^MD237/+ adults expressing l(3)L0539^EP3523 under the control of Scer\GAL4^pnr-MD237 show loss of scutellar macrochaetae and have a reduced scutellum.

(Pena-Rangel et al., 2002)

Co-expression of CycE^Scer\UAS.cLa does not suppress the small eye phenotype caused by expression of l(3)L0539^EP3523 under the control of Scer\GAL4^ey.PH.

(Tseng and Hariharan, 2002)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Selected as: a P{EP} insertion line that modifies the pnr^MD237/+ phenotype when expressed using Scer\GAL4^pnr-MD237.

(Pena-Rangel et al., 2002)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

l(3)L0539^EP3523

Name Synonyms

Secondary FlyBase IDs

References (3)

Report Sections

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