FB2024_03 , released June 25, 2024
Allele: Dmel\MenEP1250
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General Information
Symbol
Dmel\MenEP1250
Species
D. melanogaster
Name
FlyBase ID
FBal0130938
Feature type
allele
Associated gene
Dmel\Men
Associated Insertion(s)
P{EP}MenEP1250
Carried in Construct
Also Known As
EP(3)1250
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Bidet et al., 2003, Gene Disruption Project members, 2001-)
Progenitor genotype
Associated Insertion(s)
P{EP}MenEP1250
Cytology
Description

P{EP} insertion 127bp upstream of the Men translation initiation codon. The P{EP} element is oriented such that expression from the element results in overexpression of Men.

(Bidet et al., 2003)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of MenEP1250 under the control of Scer\GAL4da.Switch.PT consistently reduces the mortality rates in adults.

      (Paik et al., 2012)

      Expression of MenEP1250 under the control of Scer\GAL4GMR.PF results in a big eye phenotype.

      (Müller et al., 2005)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      MenEP1250, Scer\GAL4GMR.PF is an enhancer of visible phenotype of HUAS.cMa, Scer\GAL4GMR.PF

      (Müller et al., 2005)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      MenEP1250, Scer\GAL4GMR.PF is an enhancer of eye phenotype of HUAS.cMa, Scer\GAL4GMR.PF

      (Müller et al., 2005)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      MenEP1250
      Name Synonyms
      Secondary FlyBase IDs
        References (4)