FlyBase Allele Report: Dmel\Rm62[EP3607]

General Information

Symbol

Dmel\Rm62^EP3607

Species

D. melanogaster

Name

FlyBase ID

FBal0130790

Feature type

allele

Associated gene

Dmel\Rm62

Associated Insertion(s)

P{EP}Rm62^EP3607

Carried in Construct

Key Links

Genomic Maps

JBrowse

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Bidet et al., 2003, Gene Disruption Project members, 2001-)

Progenitor genotype

Associated Insertion(s)

P{EP}Rm62^EP3607

Cytology

Description

P{EP} insertion upstream of Rm62. The P{EP} element is oriented such that expression from the element should result in overexpression of Rm62.

(Bidet et al., 2003)

Allele components

Component

Use(s)

Inserted element

P{EP}

misexpression element

Regulatory region(s)

UAS

binary expression system - regulatory region

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

transposable_element_insertion_site

3R:6,007,558..6,007,558 [-]

(Cziko et al., 2009, Sofola et al., 2007, Bidet et al., 2003, Gene Disruption Project members, 2001-)

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

larval multidendritic class IV neuron | somatic clone, with Scer\GAL4^Act.PU

(Cziko et al., 2009)

Detailed Description

Statement

Reference

Over-expression of Rm62^EP3607 reduces dendrite branching, and alters dendritic morphology in larval class IV sensory neurons (induced under the control of Scer\GAL4^Act.PU). Total dendrite length is significantly reduced in these neurons.

(Cziko et al., 2009)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Rm62^EP3607, Scer\GAL4^GMR.PU is a suppressor of visible | adult stage phenotype of Scer\GAL4^GMR.PU, Zzzz\CGG^90.UAS.EGFP

(Qurashi et al., 2011)

Phenotype Manifest In

Suppressor of

Statement

Reference

Rm62^EP3607, Scer\GAL4^GMR.PU is a suppressor of eye phenotype of Scer\GAL4^GMR.PU, Zzzz\CGG^90.UAS.EGFP

(Qurashi et al., 2011)

Rm62^EP3607, Scer\GAL4^GMR.PU is a suppressor of ommatidium | adult stage phenotype of Scer\GAL4^GMR.PU, Zzzz\CGG^90.UAS.EGFP

(Qurashi et al., 2011)

Rm62^EP3607, Scer\GAL4^GMR.PU is a suppressor of interommatidial bristle | adult stage phenotype of Scer\GAL4^GMR.PU, Zzzz\CGG^90.UAS.EGFP

(Qurashi et al., 2011)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

The eye degeneration phenotype (rough eye with disorganized ommatidial lattice and interommatidial bristles) characteristic for flies expressing Zzzz\CGG^{90.Scer\UAS.T:Avic\GFP-EGFP} under the control of Scer\GAL4^GMR.PU is partially rescued by co-expression of Rm62^EP3607.

(Qurashi et al., 2011)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

Rm62^(3)3607

(Qurashi et al., 2011)

Rm62^EP3607

rm62<up>EP 3607</up>

(Sofola et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (5)

Report Sections

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