FB2024_03 , released June 25, 2024
Allele: Dmel\btlUAS.cDa
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General Information
Symbol
Dmel\btlUAS.cDa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Dossenbach
FlyBase ID
FBal0130477
Feature type
allele
Associated gene
Dmel\btl
Associated Insertion(s)
Carried in Construct
P{UAS-btl.D}
Key Links
Transgenic product class
cDNA
(Dossenbach et al., 2001)
wild_type
(Dossenbach et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Dossenbach et al., 2001)
wild_type
(Dossenbach et al., 2001)
Mutagen
in vitro construct
(Dossenbach et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-btl.D}
Cytology
Description

UAS regulatory sequences drive expression of a btl cDNA.

(Dossenbach et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
btl
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In

      axon & dorsal cluster neuron, with Scer\GAL4ato.3.6

      (Srahna et al., 2006)
      Detailed Description
      Statement
      Reference

      Expression of btlScer\UAS.cDa under the control of Scer\GAL4ato.3.6 results in decreased numbers of axons from dorsal cluster neurons crossing the optic chiasm (from 11.7 in wild type to 7.2 in btlScer\UAS.cDa neurons).

      (Srahna et al., 2006)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressed by
      NOT Enhancer of
      NOT Suppressor of
      Statement
      Reference

      btlUAS.cDa, Scer\GAL4ato.3.6 is a non-suppressor of abnormal neuroanatomy phenotype of Rac1N17.UAS, Scer\GAL4ato.3.6

      (Srahna et al., 2006)
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      Scer\GAL4ato.3.6, btlUAS.cDa has axon & dorsal cluster neuron phenotype, suppressible by Rac1N17.UAS, Scer\GAL4ato.3.6

      (Srahna et al., 2006)
      NOT Enhancer of
      Statement
      Reference

      btlUAS.cDa, Scer\GAL4ato.3.6 is a non-enhancer of axon & dorsal cluster neuron phenotype of Rac1N17.UAS, Scer\GAL4ato.3.6

      (Srahna et al., 2006)
      NOT Suppressor of
      Statement
      Reference

      btlUAS.cDa, Scer\GAL4ato.3.6 is a non-suppressor of axon & dorsal cluster neuron phenotype of Rac1N17.UAS, Scer\GAL4ato.3.6

      (Srahna et al., 2006)

      btlUAS.cDa/Scer\GAL4btl.PS is a non-suppressor of presumptive embryonic/larval tracheal system phenotype of btlH82Δ3, stumps09904b

      (Dossenbach et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Coexpression of btlScer\UAS.cDa and Rac1N17.Scer\UAS, under the control of Scer\GAL4ato.3.6, results in the dominance of the Rac1N17.Scer\UAS phenotype, with a large increase in the number of dorsal cluster neuron axons that cross the optic chiasm.

      (Srahna et al., 2006)

      Expression of btlScer\UAS.cDa under the control of Scer\GAL4btl.PS does not rescue any aspect of tracheal development in btlH82Δ3 stumps09904b double mutant embryos.

      (Dossenbach et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      btlUAS.cDa/Scer\GAL4btl.PS rescues btl95

      (Myat et al., 2005)

      btlUAS.cDa/Scer\GAL4btl.PS rescues btlH82Δ3

      (Dossenbach et al., 2001)
      Comments

      Expression of btlScer\UAS.cDa under the control of Scer\GAL4btl.PS completely restores tracheal morphogenesis in btlH82Δ3 embryos. All aspects of tracheal development are rescued at both 18oC and 25oC.

      (Dossenbach et al., 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      btlScer\UAS.cDa
      btlUAS.cDa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Dossenbach
      (Dossenbach et al., 2001)
      Secondary FlyBase IDs
        References (3)