FB2024_03 , released June 25, 2024
Allele: Dmel\fz1-1-1.hs.2sev
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General Information
Symbol
Dmel\fz1-1-1.hs.2sev
Species
D. melanogaster
Name
FlyBase ID
FBal0130287
Feature type
allele
Associated gene
Dmel\fz
Associated Insertion(s)
Carried in Construct
P{hs.2sev(-FRT)fz.1-1-1}
Key Links
Transgenic product class
wild_type
(Strapps and Tomlinson, 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Strapps and Tomlinson, 2001)
Mutagen
FLPase
(Strapps and Tomlinson, 2001)
Progenitor genotype
fz1-1-1.FRT.hs.2sev
(Strapps and Tomlinson, 2001)
Carried in construct
P{hs.2sev(-FRT)fz.1-1-1}
Cytology
Description

The FRT cassette has been excised, juxtaposing the sev enhancers and heat shock promoter with the fz coding sequences.

(Strapps and Tomlinson, 2001)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
fz
Also carries
FRT
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of fz1-1-1.hs.2sev in an otherwise wild-type background does not result in a dominant fz phenotype in the eye.

      (Strapps and Tomlinson, 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      fz1-1-1.hs.2sev rescues fz37/fz15

      (Strapps and Tomlinson, 2001)
      Comments

      Significantly rescues the tissue polarity defect seen in fz37/fz15 eyes, such that 86.0 +/- 5.1 % of ommatidia have the correct chiral shape.

      (Strapps and Tomlinson, 2001)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      fz1-1-1.hs.2sev
      Name Synonyms
      Secondary FlyBase IDs
        References (1)