Mosaic animals in which the retina is homozygous (generated using the "eyFLP" system) show photoreceptor projection defects. The R1-R6 and R8 axons all terminate in their correct target layers. R7 axons reach the medulla, but most stop short of their normal target, generally stopping in the same layer as the R8 axons. 40% of homozygous R7 photoreceptor axons in a Lar⁺ background (generated using P{GMR-FLP1.P}) terminate in the same layer as R8 axons, with the remaining 60% terminating in or near their correct target layer, though some termini have abnormally thin and extended morphology. 93% of homozygous R7 photoreceptor axons in a Lar⁺ background generated using P{ey-FLP.N} show mistargeting of R7 axons. The difference in frequency of mistargeting may be due to perdurance of Lar⁺ protein in homozygous R7 cells induced by P{GMR-FLP1.P} (which induces clones later than P{ey-FLP.N}) or it may reflect a non-autonomous function of Lar⁺ in R8 cells, since in clones generated by P{GMR-FLP1.P} R8 is Lar⁺ while in most clones generated by P{ey-FLP.N} R8 is also Lar^-.

Lar^C219 has photoreceptor cell R7 & axon | somatic clone phenotype, suppressible by Lar::Ptp69D^{LP.GMR.Tag:SS(wg),Tag:HA}