FB2024_03 , released June 25, 2024
Allele: Hror\Otxhs.PA
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General Information
Symbol
Hror\Otxhs.PA
Species
H. roretzi
Name
heat shock construct of Adachi
FlyBase ID
FBal0125399
Feature type
allele
Associated gene
Hror\Otx
Associated Insertion(s)
Carried in Construct
P{hs-Hror\Otx.A}
Transgenic product class
wild_type
(Adachi et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Adachi et al., 2001)
Mutagen
in vitro construct
(Adachi et al., 2001)
Progenitor genotype
Carried in construct
P{hs-Hror\Otx.A}
Cytology
Description

An Hsp70 promoter drives expression of Hror\Otx.

(Adachi et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
Hror\Otx
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Overexpression of Hror\Otxhs.PA for 20 minutes at stage 7-8 results in significant transformation of the central and peripheral nervous systems. There is a dramatic suppression of the ventral nerve cord and peripheral nervous system in the trunk, while more anterior neural structures are retained or enhanced.

      (Adachi et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Hror\Otxhs.PA is a suppressor of visible | recessive phenotype of oc1

      (Adachi et al., 2001)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Hror\Otxhs.PA is a suppressor of ocellus phenotype of oc1

      (Adachi et al., 2001)

      Hror\Otxhs.PA is a suppressor of embryonic brain & commissure phenotype of oc2

      (Adachi et al., 2001)

      Hror\Otxhs.PA is a suppressor of embryonic protocerebrum phenotype of oc2

      (Adachi et al., 2001)
      NOT Suppressor of
      Statement
      Reference

      Hror\Otxhs.PA is a non-suppressor of ocellar bristle phenotype of oc1

      (Adachi et al., 2001)

      Hror\Otxhs.PA is a non-suppressor of postocellar bristle phenotype of oc1

      (Adachi et al., 2001)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      Partially rescues the embryonic brain defects of oc2 animals. Partially rescues the vertex defects of oc1 adults; rescue of ocellus lens structures but not of ocellar or postvertical bristles is seen.

      (Adachi et al., 2001)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Hror\Otxhs.PA
      Name Synonyms
      heat shock construct of Adachi
      (Adachi et al., 2001)
      Secondary FlyBase IDs
        References (1)