FB2024_03 , released June 25, 2024
Allele: Dmel\TrlEP3609
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General Information
Symbol
Dmel\TrlEP3609
Species
D. melanogaster
Name
FlyBase ID
FBal0125224
Feature type
allele
Associated gene
Dmel\Trl
Associated Insertion(s)
P{EP}TrlEP3609
Carried in Construct
Also Known As
Trl3609
Key Links
Genomic Maps

Allele class

hypomorphic allele - molecular evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - molecular evidence

(Karagodin et al., 2016)
Mutagen
P-element activity
(Gene Disruption Project members, 2001-, Katokhin et al., 2001, Katokhin et al., 2001)
Progenitor genotype
Associated Insertion(s)
P{EP}TrlEP3609
Cytology
Description

Caused by the insertion of the P{EP} transposon into the 5'-noncoding region of the Trl gene in the vicinity of the third transcription start site, resulting in aberrant Trl splicing, formation of chimeric RNA and reduction in the amount of normal Trl transcripts.

(Karagodin et al., 2016)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Lethality occurs at hatching.

      (Katokhin et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Trl3609
      (Ogienko et al., 2020, Karagodin et al., 2016)
      TrlEP3609
      TrlEP(3)3609
      (Katokhin et al., 2001)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)