FB2024_03 , released June 25, 2024
Allele: Mmus\Nkd1UAS.Tag:MYC
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General Information
Symbol
Mmus\Nkd1UAS.Tag:MYC
Species
M. musculus
Name
FlyBase ID
FBal0124152
Feature type
allele
Associated gene
Mmus\Nkd1
Associated Insertion(s)
Carried in Construct
P{UAS-mNkd1.T:Hsap\MYC}
Transgenic product class
wild_type
(Wharton et al., 2001)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Wharton et al., 2001)
Mutagen
in vitro construct
(Wharton et al., 2001)
Progenitor genotype
Carried in construct
P{UAS-mNkd1.T:Hsap\MYC}
Cytology
Description

UAS sequences drive expression of Mmus\Nkd1 tagged with Tag:MYC.

(Wharton et al., 2001)
Allele components
Component
Use(s)
Regulatory region(s)
UAS
Encoded product / tool
Mmus\Nkd1
Tagged with
Tag:MYC
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      When Mmus\Nkd1Scer\UAS.T:Hsap\MYC is driven by Scer\GAL4B119 adults are seen with missing hemisternite bristles clusters or tha have laterally displaced sternite bristles. When Mmus\Nkd1Scer\UAS.T:Hsap\MYC is driven by Scer\GAL4l(2)E105-E105 less than 1% adults are produced that have leg truncations.

      (Wharton et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference

      The addition of wgunspecified, to Mmus\Nkd1Scer\UAS.T:Hsap\MYC, Scer\GAL4B119 flies leads to flies that have a consistent loss of hemisternite bristles clusters, some adults completely lack sternite bristles. The addition of wgunspecified, to Mmus\Nkd1Scer\UAS.T:Hsap\MYC, Scer\GAL4l(2)E105-E105 flies leads to about 12% of adults with at least one truncated leg.

      (Wharton et al., 2001)
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Mmus\Nkd1Scer\UAS.T:Hsap\MYC
      Mmus\Nkd1UAS.Tag:MYC
      Name Synonyms
      Secondary FlyBase IDs
        References (1)