FlyBase Allele Report: Dmel\dom[14]

General Information

Symbol

Dmel\dom¹⁴

Species

D. melanogaster

Name

FlyBase ID

FBal0123009

Feature type

allele

Associated gene

Dmel\dom

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

amorphic allele - genetic evidence

Mutagen

Delta2-3 transposase

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Ruhf et al., 2001)

Mutagen

Delta2-3 transposase

(Ruhf et al., 2001)

Progenitor genotype

dom^k08108

(Ruhf et al., 2001)

Cytology

Description

The P{lacW} hss excised taking with it 1649bp of genomic DNA 3' to the insertion site in progenitor P{lacW}dom^k08108. The deleted DNA includes exons 2 and 3.

(Ruhf et al., 2001)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

embryonic/larval lymph gland

(Ruhf et al., 2001)

imaginal disc

(Ruhf et al., 2001)

Detailed Description

Statement

Reference

Homozygotes die in the L1 or L2 larval stages. Larvae are small and show blackened lymph glands and no imaginal discs. Females with germline clones do not lay eggs.

(Ruhf et al., 2001)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhancer of

Statement

Reference

dom¹⁴/dom[+] is an enhancer of visible | homeotic phenotype of E(z)⁶⁰

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of visible | dominant | homeotic phenotype of ph-p⁴¹⁰

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of visible | homeotic phenotype of Pc¹⁶

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of visible | homeotic phenotype of mxc^G43

(Ruhf et al., 2001)

NOT Enhancer of

Statement

Reference

dom¹⁴/dom[+] is a non-enhancer of visible | homeotic phenotype of Scm^D1

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a non-enhancer of visible | homeotic phenotype of Psc¹

(Ruhf et al., 2001)

Suppressor of

Statement

Reference

dom¹⁴/dom[+] is a suppressor of visible | dominant | homeotic phenotype of brm[+]/brm², trx^E2

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of visible | homeotic phenotype of ash1^B1

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of visible | homeotic phenotype of brm²

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of visible | homeotic phenotype of trx^E2

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of visible | dominant | homeotic phenotype of ash1[+]/ash1¹⁷, trx^B11

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of visible | dominant | homeotic phenotype of ash1¹⁷, trx^B11/trx[+]

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of visible | dominant | homeotic phenotype of brm², trx[+]/trx^E2

(Ruhf et al., 2001)

Phenotype Manifest In

Enhancer of

Statement

Reference

dom¹⁴/dom[+] is an enhancer of mesothoracic leg phenotype of E(z)⁶⁰

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of mesothoracic leg phenotype of mxc^G43

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of metathoracic leg phenotype of mxc^G43

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of abdominal segment 6 phenotype of ph-p⁴¹⁰

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of mesothoracic leg phenotype of ph-p⁴¹⁰

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of metathoracic leg phenotype of ph-p⁴¹⁰

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of mesothoracic leg phenotype of Pc¹⁶

(Ruhf et al., 2001)

dom¹⁴/dom[+] is an enhancer of metathoracic leg phenotype of Pc¹⁶

(Ruhf et al., 2001)

NOT Enhancer of

Statement

Reference

dom¹⁴/dom[+] is a non-enhancer of mesothoracic leg phenotype of Scm^D1

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a non-enhancer of mesothoracic leg phenotype of Psc¹

(Ruhf et al., 2001)

Suppressor of

Statement

Reference

dom¹⁴/dom[+] is a suppressor of abdominal segment 6 phenotype of brm[+]/brm², trx^E2

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of abdominal segment 6 phenotype of ash1^B1

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of abdominal segment 6 phenotype of brm²

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of abdominal segment 6 phenotype of trx^E2

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of haltere phenotype of brm[+]/brm², trx^E2

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of abdominal segment 6 phenotype of ash1[+]/ash1¹⁷, trx^B11

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of abdominal segment 6 phenotype of ash1¹⁷, trx^B11/trx[+]

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of abdominal segment 6 phenotype of brm², trx[+]/trx^E2

(Ruhf et al., 2001)

dom¹⁴/dom[+] is a suppressor of haltere phenotype of brm², trx[+]/trx^E2

(Ruhf et al., 2001)

Additional Comments

Genetic Interactions

Statement

Reference

The abdominal segment A6 to A5 transformation of ash1¹⁷/+, trx^B11/+ is dominantly suppressed by dom¹⁴. The abdominal segment A6 to A5 transformation and the haltere to wing transformation of brm²/+, trx^E2/+ is dominantly suppressed by dom¹⁴.

(Ruhf et al., 2001)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

dom¹⁴

(Rust et al., 2018)

Name Synonyms

Secondary FlyBase IDs

References (2)

Report Sections

Open Close