FB2024_03 , released June 25, 2024
Allele: Dmel\msk1
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General Information
Symbol
Dmel\msk1
Species
D. melanogaster
Name
FlyBase ID
FBal0122951
Feature type
allele
Associated gene
Dmel\msk
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Baker et al., 2002)
Progenitor genotype
Cytology
Description

No change detected in the coding sequence.

(Baker et al., 2002)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most homozygotes die as pupae.

      (Baker et al., 2002)

      Lethality acts in the late embryo or early larval stages. Embryos are morphologically wild type.

      (Lorenzen et al., 2001)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Enhancer of
      Statement
      Reference

      msk1/msk[+] is an enhancer of visible phenotype of rl1

      (Lorenzen et al., 2001)
      Suppressor of
      Statement
      Reference

      msk1/msk[+] is a suppressor of visible phenotype of Scer\GAL4c684, ifm8.UAS

      (Baker et al., 2002)
      Phenotype Manifest In
      Enhancer of
      Statement
      Reference

      msk1/msk[+] is an enhancer of wing vein L4 phenotype of rl1

      (Lorenzen et al., 2001)
      Suppressor of
      Statement
      Reference

      msk1/msk[+] is a suppressor of wing phenotype of Scer\GAL4c684, ifm8.UAS

      (Baker et al., 2002)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The wing blistering caused by expression of ifm8.Scer\UAS under the control of Scer\GAL4337Y is suppressed by msk1/+.

      (Baker et al., 2002)

      Enhancing effect of msk1 and msk2 on the rl1 phenotype is marked and that of msk5 is dramatic.

      (Lorenzen et al., 2001)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer

      Selected as: a dominant suppressor of the wing blister phenotype caused by ifm8.Scer\UAS expressed under the control of Scer\GAL4c684.

      (Baker et al., 2002)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      msk1
      Name Synonyms
      Secondary FlyBase IDs
        References (2)