Amino acid replacement: Q7term.
C21025002T
Q7term | skd-PC; Q7term | skd-PD; Q7term | skd-PE; Q7term | skd-PF
Q7term
Site of nucleotide substitution in mutant inferred by FlyBase based on reported amino acid change.
Generation of skdT606 clones specifically in the leg (using Scer\GAL4Dll-em212 and Scer\FLP1Scer\UAS.cUa) and in a Minute background results in severely stunted legs. In an other wild type background, these clones result in tarsal segmentation defects in all three paris of adult legs. Male prothoracic (T1) legs exhibit sex combs with slightly reduced teeth number but mostly aligned sex combs. Legs show strong distal leg shortening, and the most proximal tarsal joint as well as more distal joints are usually abnormal.
Generation of large skdT606 clones specifically in the eye (using Scer\FLP1ey.PB) in a Minute background results in the eye failing to differentiate ommatidia.
Heat-induced ktoT241 clones in the adult notum are associated with loss of bristles.
skdT606 clones in the anterior compartment of the wing disc which touch the anterior-posterior boundary cross the boundary in 58% of cases. skdT606 clones in the wing disc (induced in the first or early second larval instar) that span the dorsal-ventral (DV) boundary often move into one of the two compartments, distorting the compartment boundary. Of skdT606 clones that touch the DV boundary, 41% push the boundary ventrally and 18% push the boundary dorsally.
Clones in the eye contain few or no photoreceptors. The few that remain are found in posterior regions of the clone, and die later in development. Clone size is normal and clones do not interfere with the spread of differentiation-promoting signals. Antennal disc cell fates are also altered.
Scer\GAL4Mef2.PR, armHMS01414, skd[+]/skdT606 has lethal phenotype
skdT606 has eye disc phenotype, non-suppressible by hhUAS.cAa/Scer\GAL4ey.PH
skdT606 has eye disc phenotype, non-suppressible by Delta::NΔECN.UAS/Scer\GAL4ey.PH
skdT606 has eye disc phenotype, non-suppressible by cim1-4.UAS.Tag:HA/Scer\GAL4ey.PH
skdT606 has photoreceptor neuron phenotype, non-suppressible by Delta::NΔECN.UAS/Scer\GAL4ey.PH
skdT606 has photoreceptor neuron phenotype, non-suppressible by cim1-4.UAS.Tag:HA/Scer\GAL4ey.PH
skdT606 has photoreceptor neuron phenotype, non-suppressible by hhUAS.cAa/Scer\GAL4ey.PH
Scer\GAL4Mef2.PR, skd[+], skdT606 is an enhancer of embryonic somatic muscle cell phenotype of armHMS01414
skdT13/skdT606 is partially rescued by skdUAS.cJa/Scer\GAL4da.G32
skdT13/skdT606 is partially rescued by skdUAS.cJa/Scer\GAL4αTub84B.PL