FB2024_03 , released June 25, 2024
Allele: Dmel\Bin1EP3462
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General Information
Symbol
Dmel\Bin1EP3462
Species
D. melanogaster
Name
FlyBase ID
FBal0121004
Feature type
allele
Associated gene
Dmel\Bin1
Associated Insertion(s)
P{EP}sraEP3462
Carried in Construct
Also Known As
EP(3)3462
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
P-element activity
(Singh, 2002.3.20, Zhu et al., 2001, Espinas et al., 2000)
Progenitor genotype
Associated Insertion(s)
P{EP}sraEP3462
Cytology
Description

P{EP} is inserted 259 bp from start codon of Bin1.

(Singh, 2002.3.20)

P{EP} insertion 259bp upstream of the start codon and 151bp upstream of the transcription start site. The P{EP} element is oriented so that expression from the Scer\UAS regulatory sequences in the element will drive overexpression of Bin1.

(Zhu et al., 2001)

P{EP} insertion in the 5' UTR.

(Espinas et al., 2000)
Allele components
Component
Use(s)
Inserted element
P{EP}
Regulatory region(s)
UAS
Mutations Mapped to the Genome
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      62% of Bin1EP3462/Df(3R)sbd45 males show transformation of A6 to A5, as judged by the presence of at least one bristle on the sixth sternite.

      (Canudas et al., 2005)

      Bin1EP3462/Df(3R)sbd26 males show homeotic transformation of the sixth abdominal segment into the fifth, as shown by the presence of more than 2 bristles in the sixth sternite in 71% flies.

      (Espinas et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Bin1EP3462/Trlunspecified double heterozygotes do not show a homeotic phenotype.

      (Espinas et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Bin1EP3462
      EP(3)3462
      (Zhu et al., 2001, Espinas et al., 2000)
      Name Synonyms
      Secondary FlyBase IDs
        References (6)