FB2024_03 , released June 25, 2024
Allele: Dmel\fzsev.PT
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General Information
Symbol
Dmel\fzsev.PT
Species
D. melanogaster
Name
sevenless promoter construct of Tomlinson
FlyBase ID
FBal0103814
Feature type
allele
Associated gene
Dmel\fz
Associated Insertion(s)
Carried in Construct
P{1Xsev-fz.T}
Key Links
Transgenic product class
wild_type
(Tomlinson and Struhl, 1999)
Mutagen
Nature of the Allele
Transgenic product class
wild_type
(Tomlinson and Struhl, 1999)
Mutagen
in vitro construct
(Tomlinson and Struhl, 1999)
Progenitor genotype
Carried in construct
P{1Xsev-fz.T}
Cytology
Description

One copy of the sev enhancer is fused upstream of the sev promoter driving fz expression.

(Tomlinson and Struhl, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
sev
Encoded product / tool
fz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye development appears normal in flies carrying one copy of fzsev.PT. Ommatidia show a normal chirality pattern, except for rare (less than 5%) ommatidia with incorrect chirality.

      (Tomlinson and Struhl, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      fzsev.PT partially rescues fz15

      (Tomlinson and Struhl, 1999)

      fzsev.PT partially rescues fz37

      (Tomlinson and Struhl, 1999)
      Comments

      Fully rescues the rough eye phenotype but does not rescue the fz- body phenotype of fz15 or fz37 flies.

      (Tomlinson and Struhl, 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      fzsev.PT
      Name Synonyms
      sevenless promoter construct of Tomlinson
      (Tomlinson and Struhl, 1999)
      Secondary FlyBase IDs
        References (1)