FB2024_03 , released June 25, 2024
Allele: Dmel\msl-1Δ84C.hs
Open Close
General Information
Symbol
Dmel\msl-1Δ84C.hs
Species
D. melanogaster
Name
FlyBase ID
FBal0103654
Feature type
allele
Associated gene
Dmel\msl-1
Associated Insertion(s)
Carried in Construct
P{Δ84C.msl-1}
Key Links
Transgenic product class
inframe_deletion
(Scott et al., 2000)
Mutagen
Nature of the Allele
Transgenic product class
inframe_deletion
(Scott et al., 2000)
Mutagen
in vitro construct
(Scott et al., 2000)
Progenitor genotype
msl-1Δ84.hs
(Scott et al., 2000)
Carried in construct
P{Δ84C.msl-1}
Cytology
Description

The C terminus from amino acid 760 to 1039 has been deleted.

(Scott et al., 2000)
Allele components
Component
Use(s)
Regulatory region(s)
Hsp70
Encoded product / tool
msl-1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      There is a significant loss of male viability (about 2/5 of expected males survive) in homozygous mutants where expression of msl-1Δ84C.hs in induced by heatshock.

      (Scott et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Suppressed by
      Statement
      Reference

      msl-1Δ84C.hs has phenotype, suppressible by msl-2Hsp83.PK

      (Scott et al., 2000)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The addition of msl-2Hsp83.PK suppresses the male viability phenotype seen in heatshocked msl-1Δ84C.hs flies.

      (Scott et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      msl-1Δ84C'*'.hs
      msl-1Δ84C.hs
      Name Synonyms
      Secondary FlyBase IDs
        References (1)