FlyBase Allele Report: Hsap\VGLL1[UAS.cVa]

General Information

Symbol

Hsap\VGLL1^UAS.cVa

Species

H. sapiens

Name

Saccharomyces cerevisiae UAS construct a of Vaudin

FlyBase ID

FBal0102975

Feature type

allele

Associated gene

Hsap\VGLL1

Associated Insertion(s)

Carried in Construct

P{UAS-Hsap\TDU.V}

Key Links

Transgenic product class

wild_type

(Vaudin et al., 1999)

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

wild_type

(Vaudin et al., 1999)

Mutagen

in vitro construct

(Vaudin et al., 1999)

Progenitor genotype

Carried in construct

P{UAS-Hsap\TDU.V}

Cytology

Description

UASt regulatory sequences drive expression of Hsap\VGLL1.

(Vaudin et al., 1999)

Allele components

Component

Use(s)

Regulatory region(s)

UASt

binary expression system - regulatory region

Encoded product / tool

Hsap\VGLL1

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible, with Scer\GAL4^da.G32

(Vaudin et al., 1999)

visible, with Scer\GAL4^ptc-559.1

(Vaudin et al., 1999)

Phenotype Manifest In

eye, with Scer\GAL4^da.G32

(Vaudin et al., 1999)

eye, with Scer\GAL4^ptc-559.1

(Vaudin et al., 1999)

Detailed Description

Statement

Reference

Expression of Hsap\TDU^Scer\UAS.cVa under the control of Scer\GAL4^ptc-559.1 or Scer\GAL4^da.G32 results in a large increase in eye size.

(Vaudin et al., 1999)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressor of

Statement

Reference

Hsap\VGLL1^UAS.cVa/Scer\GAL4^vg.int2.1 is a suppressor of visible | recessive phenotype of vg^83b27

(Vaudin et al., 1999)

Phenotype Manifest In

Suppressed by

Statement

Reference

Hsap\VGLL1^UAS.cVa, Scer\GAL4^ptc-559.1 has eye phenotype, suppressible by sd^ETX4

(Vaudin et al., 1999)

Hsap\VGLL1^UAS.cVa, Scer\GAL4^da.G32 has eye phenotype, suppressible by sd^ETX4

(Vaudin et al., 1999)

Suppressor of

Statement

Reference

Hsap\VGLL1^UAS.cVa/Scer\GAL4^vg.int2.1 is a suppressor of wing phenotype of vg^83b27

(Vaudin et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Partial, but significant rescue of the vg^83b27 lack of wing phenotype is seen when Hsap\TDU^Scer\UAS.cVa is expressed under the control of Scer\GAL4^vg.int2.1. The rescued wings have veins and wing margins. The increase in eye size seen in flies expressing Hsap\TDU^Scer\UAS.cVa under the control of Scer\GAL4^ptc-559.1 or Scer\GAL4^da.G32 is partially suppressed in a sd^ETX4 background.

(Vaudin et al., 1999)

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (4)

Reported As

Symbol Synonym

Hsap\TDU^Scer\UAS.cVa

Hsap\VGLL1^Scer\UAS.cVa

Hsap\VGLL1^UAS.cVa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of Vaudin

(Vaudin et al., 1999)

Secondary FlyBase IDs

References (1)

Report Sections

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