FB2024_03 , released June 25, 2024
Allele: Dmel\Cdk1UAS.cHa
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General Information
Symbol
Dmel\Cdk1UAS.cHa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Hayashi
FlyBase ID
FBal0097040
Feature type
allele
Associated gene
Dmel\Cdk1
Associated Insertion(s)
Carried in Construct
P{UAS-Cdk1.H}
Key Links
Transgenic product class
cDNA
(Hayashi and Yamaguchi, 1999)
wild_type
(Hayashi and Yamaguchi, 1999)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Hayashi and Yamaguchi, 1999)
wild_type
(Hayashi and Yamaguchi, 1999)
Mutagen
in vitro construct
(Hayashi and Yamaguchi, 1999)
Progenitor genotype
Carried in construct
P{UAS-Cdk1.H}
Cytology
Description

A Cdk1 cDNA is expressed under the control of UASt regulatory sequences.

(Hayashi and Yamaguchi, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
Cdk1
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of cdc2Scer\UAS.cHa in the salivary glands under the control of Scer\GAL4l(1)BP-1 has very little effect on endoreplication at 25oC.

      (Hayashi and Yamaguchi, 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Expression of both CycAScer\UAS.cHa and cdc2Scer\UAS.cHa in the salivary glands under the control of Scer\GAL4l(1)BP-1 strongly prevents endoreplication and growth in the salivary glands. The inhibition of endoreplication in the salivary gland caused by coexpression of both CycAScer\UAS.cHa and cdc2Scer\UAS.cHa under the control of Scer\GAL4l(1)BP-1 is reversed if the larvae are also expressing E2fhs.PA.

      (Hayashi and Yamaguchi, 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Carried in a plasmid, transfected into Kc cells and used in transcription activation assays.

      (Hayashi and Yamaguchi, 1999)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (4)
      Reported As
      Symbol Synonym
      Cdk1Scer\UAS.cHa
      Cdk1UAS.cHa
      cdc2Scer\UAS.cHa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Hayashi
      (Hayashi and Yamaguchi, 1999)
      Secondary FlyBase IDs
        References (1)