FB2024_03 , released June 25, 2024
Allele: Dmel\dve5.0.UAS
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General Information
Symbol
Dmel\dve5.0.UAS
Species
D. melanogaster
Name
FlyBase ID
FBal0096985
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
UAS-dve
Key Links
Transgenic product class
Nature of the Allele
Transgenic product class
Progenitor genotype
Carried in construct
Cytology
Description

A 5.0kb XhoI/Xba fragment which includes the open reading frame of the 5.0kb dve transcript (including intron 3) is expressed under the control of UASt regulatory sequences.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Expression of dve5.0.Scer\UAS in the cells of the dorsal anterior/posterior boundary of the leg using Scer\GAL4bi-md653 blocks the formation dorsal parts of the joints in the tarsal regions pharate adult legs.

Clones in the wing disc expressing dve5.0.Scer\UAS under the control of Scer\GAL4Act5C.PI cause the formation of folds around the clone.

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Suppressor of
Statement
Reference
NOT Suppressor of
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments

The lethality of dve01738/dveBG02382 animals is rescued by expression of dve5.0.Scer\UAS under the control of Scer\GAL4dve-BG02382. These "rescued" animals have a wing phenotype that is slightly weaker than that of dve01738 homozygotes.

Completely rescues the proventriculus phenotype of dve01738 embryos when expressed under the control of Scer\GAL4fkh.14-3.

Images (0)
Mutant
Wild-type
Stocks (1)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
dve5.0.Scer\UAS
dve5.0.UAS
Name Synonyms
Secondary FlyBase IDs
    References (5)