FB2024_03 , released June 25, 2024
Allele: Dmel\sns43-49
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General Information
Symbol
Dmel\sns43-49
Species
D. melanogaster
Name
FlyBase ID
FBal0095913
Feature type
allele
Associated gene
Dmel\sns
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
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        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Fusion of developing muscles is abnormal in homozygous embryos.

        (Paululat et al., 1999)

        Dorsal vessel and visceral mesoderm is unaffected in embryos homozygous for the "rost30A" chromosome (carrying both rost30A and sns43-49 but major distortions occur in somatic mesoderm. Late stages of embryonic development show many unfused myoblasts. First distortions are visible during germ-band retraction. Unfused myoblasts are often arranged in specific locations where in the wild type ventral, pleural and longitudinal muscles form.

        (Paululat et al., 1995)
        External Data
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        Show genetic interaction network for Enhancers & Suppressors
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        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Images (0)
        Mutant
        Wild-type
        Stocks (0)
        Notes on Origin
        Discoverer

        Separable from: rost30A. The "rost30A" chromosome contains mutations in two genes that affect muscle fusion. One mutation is in rost (rost30A) and the other is sns43-49.

        (Paululat et al., 1999)

        Separable from: rost30A.

        (Paululat et al., 1999)
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (3)
        Reported As
        Symbol Synonym
        43-49
        (Bour et al., 2000, Paululat et al., 1999, Paululat et al., 1999)
        43-4943-49
        sns43-49
        Name Synonyms
        Secondary FlyBase IDs
          References (4)