FB2024_03 , released June 25, 2024
Allele: Dmel\Prosβ2+t2.7
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General Information
Symbol
Dmel\Prosβ2+t2.7
Species
D. melanogaster
Name
FlyBase ID
FBal0095638
Feature type
allele
Associated gene
Dmel\Prosβ2
Associated Insertion(s)
Carried in Construct
P{Prosβ2+t2.7}
Key Links
Genomic Maps

Transgenic product class
genomic_DNA
(Smyth and Belote, 1999)
wild_type
(Smyth and Belote, 1999)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Smyth and Belote, 1999)
wild_type
(Smyth and Belote, 1999)
Mutagen
in vitro construct
(Smyth and Belote, 1999)
Progenitor genotype
Carried in construct
P{Prosβ2+t2.7}
Cytology
Description

Contains a 2.7kb EcoRI/PstI fragment containing the wild-type Prosβ2 gene, approximately 0.9kb of 5' upstream sequences and 0.5kb of 3' downstream sequences.

(Smyth and Belote, 1999)
Allele components
Component
Use(s)
Regulatory region(s)
Prosβ2
Encoded product / tool
Prosβ2
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
rescue_region
3L:14,999,002..15,001,779 [+]
Linked to:
PstI-EcoRI restriction fragment
Comment:

Position of restriction fragment on reference sequence inferred by FlyBase curator.

(Labourier et al., 2002)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Prosβ2+t2.7 rescues Prosβ2rv11γ

      (Smyth and Belote, 1999)

      Prosβ2+t2.7 rescues Prosβ2rv12γ

      (Smyth and Belote, 1999)

      Prosβ2+t2.7 rescues Prosβ2rv3γ

      (Smyth and Belote, 1999)

      Prosβ2+t2.7 rescues Prosβ2rv3D

      (Smyth and Belote, 1999)

      Prosβ2+t2.7 rescues Prosβ21

      (Smyth and Belote, 1999)
      Fails to rescue

      Prosβ2+t2.7 fails to rescue Prosβ2rv19X

      (Smyth and Belote, 1999)
      Comments

      Rescues the dominant temperature sensitive lethality of Prosβ21. Rescues the recessive lethality of Prosβ2rv3D, Prosβ2rv3γ, Prosβ2rv11γ and Prosβ2rv12γ. Fails to rescue the recessive lethality of Prosβ2rv19X.

      (Smyth and Belote, 1999)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      Prosβ2+t2.7
      Name Synonyms
      Secondary FlyBase IDs
        References (1)