FlyBase Allele Report: Dmel\ap::Lim3[UAS.cOa]

General Information

Symbol

Dmel\ap::Lim3^UAS.cOa

Species

D. melanogaster

Name

Saccharomyces cerevisiae UAS construct a of O'Keefe

FlyBase ID

FBal0095527

Feature type

allele

Associated gene

ap::Lim3

Associated Insertion(s)

Carried in Construct

P{UAS-ap::Lim3.O}

Key Links

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(O'Keefe et al., 1998)

Progenitor genotype

Carried in construct

P{UAS-ap::Lim3.O}

Cytology

Description

UAS regulatory sequences drive expression of a chimeric protein consisting of amino acids 1 to 169 of Lim3 (includes the LIM domains) fused to amino acids 339 to 470 of ap (includes the homeodomain).

(O'Keefe et al., 1998)

Allele components

Component

Use(s)

Regulatory region(s)

UAS

binary expression system - regulatory region

Encoded product / tool

ap::Lim3

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

Scer\GAL4^ap-md544/ap::Lim3^UAS.cOa is a suppressor of tarsal segment 4 phenotype of ap^md544/ap^UGO35

(Pueyo and Couso, 2004)

Scer\GAL4^ap-md544/ap::Lim3^UAS.cOa is a suppressor of pretarsus phenotype of ap^md544/ap^UGO35

(Pueyo and Couso, 2004)

ap::Lim3^UAS.cOa, Scer\GAL4^ap-md544 is a suppressor of tarsal segment 4 phenotype of Bar^UAS.cKa, Scer\GAL4^ap-md544

(Pueyo and Couso, 2004)

Scer\GAL4^ap-md544/ap::Lim3^UAS.cOa is a suppressor | partially of wing phenotype of ap^md544/ap^P44

(O'Keefe et al., 1998)

Scer\GAL4^ap-md544/ap::Lim3^UAS.cOa is a suppressor | partially of larval longitudinal connective phenotype of ap^md544/ap^P44

(O'Keefe et al., 1998)

Additional Comments

Genetic Interactions

Statement

Reference

ap::Lim3^Scer\UAS.cOa; Scer\GAL4^ap-md544 suppresses fusion of tarsal segments 4 and 5 in ap^UGO35/ap^md544 flies. The loss of tarsal segment 4 in the legs of B^Scer\UAS.cKa; Scer\GAL4^ap-md544 flies is suppressed by ap::Lim3^Scer\UAS.cOa.

(Pueyo and Couso, 2004)

The wing, sterility and uncoordinated behaviour phenotypes of ap^md544/ap^P44 flies are rescued by ap::Lim3^Scer\UAS.cOa expressed under the control of Scer\GAL4^ap-md544 to the same extent as the rescue seen by ap^Scer\UAS.cOa. In contrast, the axon pathfinding phenotype of ap^md544/ap^P44 embryos is only partially rescued by ap::Lim3^Scer\UAS.cOa expressed under the control of Scer\GAL4^ap-md544.

(O'Keefe et al., 1998)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (3)

Reported As

Symbol Synonym

ap::Lim3^Scer\UAS.cOa

ap::Lim3^UAS.cOa

Name Synonyms

Saccharomyces cerevisiae UAS construct a of O'Keefe

(O'Keefe et al., 1998)

Secondary FlyBase IDs

References (2)

Report Sections

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