FB2024_03 , released June 25, 2024
Allele: Dmel\EcR225
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General Information
Symbol
Dmel\EcR225
Species
D. melanogaster
Name
FlyBase ID
FBal0090697
Feature type
allele
Associated gene
Dmel\EcR
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
Delta2-3 transposase
(Schubiger et al., 1998)
Progenitor genotype
EcRk04504
(Schubiger et al., 1998)
Cytology
Description

Carries a ~2.8kb deletion centred on the P{lacW}EcRk04504 insertion site, and a 25bp insertion and a 19bp deletion located ~1.4kb downstream of the insertion.

(Carney et al., 2004)

Imprecise excision of the P{lacW} element, resulting in a 2.6kb deletion that removes the EcR-B transcription start site.

(Schubiger et al., 1998)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Most EcR225/EcRM554fs animals fail to survive to the second larval instar stage and few mutant animals survive to the 3rd larval instar stage.

      (Schubiger et al., 1998)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      EcR[+]/EcR225 is a suppressor | partially of lethal phenotype of ari-13747

      (Gradilla et al., 2011)

      EcR[+]/EcR225 is a suppressor of visible phenotype of Atg1UAS.cCa, Scer\GAL4ptc-559.1

      (Chen et al., 2008)

      EcR[+]/EcR225 is a suppressor of visible phenotype of PaxUAS.cCa, Scer\GAL432B

      (Chen et al., 2008)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      EcR[+]/EcR225 is a suppressor of anterior crossvein phenotype of Atg1UAS.cCa, Scer\GAL4ptc-559.1

      (Chen et al., 2008)

      EcR[+]/EcR225 is a suppressor of wing hair phenotype of Atg1UAS.cCa, Scer\GAL4ptc-559.1

      (Chen et al., 2008)

      EcR[+]/EcR225 is a suppressor of wing phenotype of PaxUAS.cCa, Scer\GAL432B

      (Chen et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      One copy of EcR225 significantly suppresses the Scer\GAL432B-driven PaxScer\UAS.cCa-induced wing blistering.

      One copy of EcR225 suppresses the Scer\GAL4ptc-559.1-driven Atg1Scer\UAS.cCa-induced wing defects.

      (Chen et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      EcR225
      (Santhanam et al., 2014, Gradilla et al., 2011, Chen et al., 2008, Schuldiner et al., 2008)
      Name Synonyms
      Secondary FlyBase IDs
        References (7)