FlyBase Allele Report: Dmel\dec[VA28]

General Information

Symbol

Dmel\dec^VA28

Species

D. melanogaster

Name

FlyBase ID

FBal0089355

Feature type

allele

Associated gene

Dmel\dec

Associated Insertion(s)

Carried in Construct

Also Known As

dec-1^VA28

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

egg chorion

(Stein et al., 2008)

Detailed Description

Statement

Reference

Chorion produced by dec-1^VA28 mutant cells appears transparent compared to chorion produced by wild-type cells.

(Stein et al., 2008)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Other

Statement

Reference

dec^VA28, pip² has abnormal planar polarity phenotype

(Stein et al., 2008)

Phenotype Manifest In

NOT Enhancer of

Statement

Reference

dec-1[+]/dec^VA28 is a non-enhancer | maternal effect of embryonic/first instar larval cuticle | maternal effect phenotype of pip⁷/pip²

(Zhang et al., 2009)

Other

Statement

Reference

dec^VA28, pip² has embryo phenotype

(Stein et al., 2008)

Additional Comments

Genetic Interactions

Statement

Reference

The severity of the dorsalisation phenotype seen in embryos derived from pip²/pip⁷ females is not increased if the females are also carrying dec-1^VA28/+.

(Zhang et al., 2009)

pip², dec-1^VA28 double mutant clones exhibit perturbations in the dorso-ventral axis of most of the embryos derived from egg chambers carrying a ventral clone of mutant follicle cells. Dorsalized phenotypes include a narrowing of the ventral denticle bands and the display of a 'tail-up' phenotype.

(Stein et al., 2008)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (4)

Bloomington

8574