FB2024_03 , released June 25, 2024
Allele: Dmel\dockUAS.cRa
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General Information
Symbol
Dmel\dockUAS.cRa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Rao
FlyBase ID
FBal0089351
Feature type
allele
Associated gene
Dmel\dock
Associated Insertion(s)
Carried in Construct
P{UAS-dock.R}
Also Known As
UAS-dock
Key Links
Transgenic product class
cDNA
(Rao and Zipursky, 1998)
wild_type
(Rao and Zipursky, 1998)
Mutagen
Nature of the Allele
Transgenic product class
cDNA
(Rao and Zipursky, 1998)
wild_type
(Rao and Zipursky, 1998)
Mutagen
in vitro construct
(Rao and Zipursky, 1998)
Progenitor genotype
Carried in construct
P{UAS-dock.R}
Cytology
Description

UASt regulatory sequences drive expression of a dock cDNA.

(Rao and Zipursky, 1998)
Allele components
Component
Use(s)
Regulatory region(s)
UASt
Encoded product / tool
dock
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Expression of dockScer\UAS.cRa under the control of Scer\GAL4GMR.PF results in a modest rough-eye phenotype.

      (Wu et al., 2011)

      Expression of dockScer\UAS.cRa under the control of Scer\GAL4GMR.PF in a wild-type background has no effect on photoreceptor cell projections.

      (Ruan et al., 1999)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      NOT Suppressor of
      Statement
      Reference

      dockUAS.cRa, Scer\GAL4GMR.PF is a non-suppressor of visible phenotype of InRUAS.cUa, Scer\GAL4GMR.PF

      (Wu et al., 2011)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Ptp61FUAS.m.Tag:MYC/dockUAS.cRa, Scer\GAL4GMR.PF is a suppressor | partially of eye phenotype of InRUAS.cUa, Scer\GAL4GMR.PF

      (Wu et al., 2011)

      Scer\GAL4GMR.PF/dockUAS.cRa is a suppressor of eye photoreceptor cell & axon phenotype of Scer\GAL4GMR.PF, msnEP549

      (Ruan et al., 1999)
      NOT Suppressor of
      Statement
      Reference

      dockUAS.cRa, Scer\GAL4GMR.PF is a non-suppressor of eye phenotype of InRUAS.cUa, Scer\GAL4GMR.PF

      (Wu et al., 2011)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      Co-expression of dockScer\UAS.cRa does not suppress the eye overgrowth phenotype caused by expression of InRScer\UAS.cUa under the control of Scer\GAL4GMR.PF.

      Co-expression of dockScer\UAS.cRa results in a further reduction in eye overgrowth in flies co-expressing both Ptp61FScer\UAS.m.T:Hsap\MYC and InRScer\UAS.cUa under the control of Scer\GAL4GMR.PF.

      (Wu et al., 2011)

      Largely suppresses the pretarget termination phenotype of photoreceptor cell axons caused by expression of msnEP549 under the control of Scer\GAL4GMR.PF.

      (Ruan et al., 1999)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescues

      Scer\GAL4elav.PLu/dockUAS.cRa rescues dock04723

      (Desai et al., 1999)

      Scer\GAL4elav.PLu/dockUAS.cRa rescues dock04723

      (Rao and Zipursky, 1998)
      Partially rescues

      Scer\GAL4SG18.1/dockUAS.cRa partially rescues dock04723

      (Ang et al., 2003)
      Comments

      Scer\GAL4SG18.1; dockScer\UAS.cRa (gives expression in olfactory neurons, but not in the brain) rescues the development of most glomeruli in the antennal lobes of dock04723 homozygous flies.

      (Ang et al., 2003)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      dockScer\UAS.cRa
      dockUAS.cRa
      Name Synonyms
      Saccharomyces cerevisiae UAS construct a of Rao
      (Rao and Zipursky, 1998)
      Secondary FlyBase IDs
        References (7)